Recombinant KDM2A Antibody - Primary antibody, specific to KDM2A, Rabbit IgG
Synonyms
[Histone-H3]-lysine-36 demethylase 1A | CXXC-type zinc finger protein 8 | CXXC8 | F box / LRR repeat protein 11 | F box and leucine rich repeat protein 11 | F box protein FBL7 | F-box and leucine-rich repeat protein 11 | F-box protein FBL7 | F-box protein
Specifications & Purity
ExactAb™, Validated, Recombinant, 1.3 mg/mL
Host species
Rabbit
Specificity
KDM2A
Immunogen
A synthetic peptide derived from human FBXL11 (AA 2-19)
Positive Control
WB: Jurkat, HeLa, K562, MCF7 and NIH/3T3 cell lysates.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Product Description
Rabbit anti Human KDM2A Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis.
Product Properties
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Antigen affinity purified
Form
Liquid
Concentration
1.3 mg/mL
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
Recombinant KDM2A Antibody (Ab111919) - Western Blot All lanes: Recombinant KDM2A Antibody (Ab111919) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 133 kDa Observed band size: 138 kDa Exposure time: 28.9 s