Recombinant KDM2A Antibody - Primary antibody, specific to KDM2A, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab111919
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab111919-10μl
10μl
In stock
$69.90
Ab111919-50μl
50μl
In stock
$199.90
Ab111919-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab111919-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

Recombinant; Rabbit anti Human KDM2A Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant KDM2A Antibody - Primary antibody, specific to KDM2A, Rabbit IgG
Synonyms[Histone-H3]-lysine-36 demethylase 1A | CXXC-type zinc finger protein 8 | CXXC8 | F box / LRR repeat protein 11 | F box and leucine rich repeat protein 11 | F box protein FBL7 | F-box and leucine-rich repeat protein 11 | F-box protein FBL7 | F-box protein
Specifications & PurityExactAb™, Validated, Recombinant, 1.3 mg/mL
Host speciesRabbit
SpecificityKDM2A
ImmunogenA synthetic peptide derived from human FBXL11 (AA 2-19)
Positive ControlWB: Jurkat, HeLa, K562, MCF7 and NIH/3T3 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human KDM2A Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function
Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodAntigen affinity purified
FormLiquid
Concentration1.3 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant KDM2A Antibody (Ab111919) - Western Blot
All lanes: Recombinant KDM2A Antibody (Ab111919) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 133 kDa
Observed band size: 138 kDa
Exposure time: 28.9 s

Associated Targets(Human)

KDM2A Tchem Lysine-specific demethylase 2A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KDM2A Tchem Lysine-specific demethylase 2A (198 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
WB

1/500-1/1000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0506079Certificate of AnalysisMay 24, 2024 Ab111919
ZJ24F0506080Certificate of AnalysisMay 24, 2024 Ab111919

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