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Recombinant Lambda Light chain Antibody - Primary antibody, specific to Lambda Light chain, Mouse IgG1

Recombinant

Validated

ExactAb™

0.02 mg/mL

Features and benefits

Short Overview:
Recombinant (MyM1-Lambda); Mouse anti Human Lambda Light chain Antibody; IHC; Unconjugated
Species reactivity(Reacts with): Human
Isotype: Mouse IgG1

Application:

Item Number

Ab112610

Grouped product items
SKU	Size	Availability	Price
Ab112610-10μl	10μl	In stock	$49.90
Ab112610-50μl	50μl	In stock	$159.90
Ab112610-100μl	100μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$219.90
Ab112610-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$899.90

Recombinant (MyM1-Lambda); Mouse anti Human Lambda Light chain Antibody; IHC; Unconjugated

View related series

Click to view target information: IGLC1 Click to view target information: IGLV1-51

Accession#: P01701 Accession#: P0CG04 Gene ID: 28820 Gene ID: 3535 Gene ID: 3537 IGL IGLC1 IGLV1-51 Lambda Light chain

Basic Description

Product Name	Recombinant Lambda Light chain Antibody - Primary antibody, specific to Lambda Light chain, Mouse IgG1
Synonyms	Bence Jones protein antibody \| BJP antibody \| Constant region of lambda light chains antibody \| Ig lambda chain C regions antibody \| ig lambda-6 chain C region antibody \| IGLC 1 antibody \| IGLC 2 antibody \| IGLC 3 antibody \| IGLC antibody \| IGLC1 antibody
Specifications & Purity	ExactAb™, Validated, Recombinant, 0.02 mg/mL
Host species	Mouse
Specificity	Lambda Light chain
Positive Control	IHC: Human tonsil tissue.
Conjugation	Unconjugated
Grade	ExactAb™, Recombinant, Validated
Product Description	Mouse anti Human Lambda Light chain Antibody, Recombinant (MyM1-Lambda), could be used for IHC and so on. Application IHC: 1/100-1/200 Relevance All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).

Product Properties

Isotype	Mouse IgG1
Light Chain Type	kappa
SDS-PAGE	150 kDa
Purification Method	Protein A purified
Form	Liquid
Concentration	0.02 mg/mL
Storage Temp	Store at 2-8°C,Freeze prohibited
Shipped In	Wet ice
Stability And Storage	Store at 2-8°C long term (36 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant Lambda Light chain Antibody (Ab112610) - IHC
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling Lambda Light chain with Recombinant Lambda Light chain Antibody (Ab112610) at 1/200 dilution. The section was incubated with Ab112610 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.

Associated Targets(Human)

IGLC1 Tdark Immunoglobulin lambda constant 1 (0 Activities)

Discover Target: IGLC1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IGLV1-51 Tdark Immunoglobulin lambda variable 1-51 (0 Activities)

Discover Target: IGLV1-51

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Application

Dilution info

IHC

1/100 - 1/200

Certificates

Certificate of Analysis(COA)

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2 results found

Lot Number	Certificate Type	Date	Item
ZJ24F0505258	Certificate of Analysis	May 09, 2024	Ab112610
ZJ24F0505257	Certificate of Analysis	May 09, 2024	Ab112610

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