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Recombinant Lambda Light chain Antibody - Primary antibody, specific to Lambda Light chain, Mouse IgG1

  • ExactAb™
  • Recombinant
  • Validated
  • 0.02 mg/mL
Features and benefits
  • Short Overview:

    Recombinant (MyM1-Lambda); Mouse anti Human Lambda Light chain Antibody; IHC; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG1
    Application:
  • IHC
Item Number
Ab112610
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab112610-10μl
10μl
In stock
$49.90
Ab112610-50μl
50μl
In stock
$159.90
Ab112610-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$219.90
Ab112610-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$899.90

Recombinant (MyM1-Lambda); Mouse anti Human Lambda Light chain Antibody; IHC; Unconjugated

Basic Description

Product NameRecombinant Lambda Light chain Antibody - Primary antibody, specific to Lambda Light chain, Mouse IgG1
Specifications & PurityExactAb™, Validated, Recombinant, 0.02 mg/mL
Host speciesMouse
SpecificityLambda Light chain
Positive ControlIHC: Human tonsil tissue.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Mouse anti Human Lambda Light chain Antibody, Recombinant (MyM1-Lambda), could be used for IHC and so on.
Application
IHC: 1/100-1/200 
Relevance
All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).

Product Properties

IsotypeMouse IgG1
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.02 mg/mL
Storage TempStore at 2-8°C,Freeze prohibited
Shipped InWet ice
Stability And StorageStore at 2-8°C long term (36 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant Lambda Light chain Antibody (Ab112610) - IHC
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling Lambda Light chain with Recombinant Lambda Light chain Antibody (Ab112610) at 1/200 dilution. The section was incubated with Ab112610 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​


Associated Targets

IGLC1 Tdark Immunoglobulin lambda constant 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

IGLV1-51 Tdark Immunoglobulin lambda variable 1-51 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
IHC

1/100 - 1/200

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0505258Certificate of AnalysisMay 09, 2024 Ab112610
ZJ24F0505257Certificate of AnalysisMay 09, 2024 Ab112610

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