Recombinant LSP1 Antibody - Primary antibody, specific to LSP1, Rabbit IgG
Synonyms
WP34 | pp5247 | kDa actin binding protein antibody | 47 kDa actin-binding protein antibody | 52 kDa phosphoprotein antibody | F actin binding and cytoskeleton associated protein antibody | Leufactin (leukocyte F-actin binding protein) antibody | Leufactin
Specifications & Purity
ExactAb™, Validated, Recombinant, 1.0 mg/mL
Host species
Rabbit
Specificity
LSP1
Immunogen
A synthetic peptide derived from human LSP1 (AA 289-339)
Positive Control
WB: Ramos, Raji and C6 cell lysates.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Product Description
Rabbit anti Human LSP1 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function: May play a role in mediating neutrophil activation and chemotaxis.
Product Properties
Isotype
Rabbit IgG
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein A purified
Form
Liquid
Concentration
1.0 mg/mL
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images
Recombinant LSP1 Antibody (Ab113672) - Western Blot All lanes: Recombinant LSP1 Antibody (Ab113672) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 37 kDa Observed band size: 36 kDa Exposure time: 61.3 s
Recombinant LSP1 Antibody (Ab113672) - Western Blot All lanes: Recombinant LSP1 Antibody (Ab113672) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 37 kDa Observed band size: 51 kDa Exposure time: 10.0 s
Associated Targets(Human)
LSP1TbioLymphocyte-specific protein 1 (0 Activities)
1.Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions.. Science, 325 (5942):(834-40). [PMID:19608861][10.1021/op500134e]
2.Todd D Taylor,Hideki Noguchi,Yasushi Totoki,Atsushi Toyoda,Yoko Kuroki,Ken Dewar,Christine Lloyd,Takehiko Itoh,Tadayuki Takeda,Dae-Won Kim,Xinwei She,Karen F Barlow,Toby Bloom,Elspeth Bruford,Jean L Chang,Christina A Cuomo,Evan Eichler,Michael G FitzGerald,David B Jaffe,Kurt LaButti,Robert Nicol,Hong-Seog Park,Christopher Seaman,Carrie Sougnez,Xiaoping Yang,Andrew R Zimmer,Michael C Zody,Bruce W Birren,Chad Nusbaum,Asao Fujiyama,Masahira Hattori,Jane Rogers,Eric S Lander,Yoshiyuki Sakaki. (2006-03-24) Human chromosome 11 DNA sequence and analysis including novel gene identification.. Nature, 440 ((7083)):(497-500). [PMID:16554811]
3.Kadiyala, R K RK, McIntyre, B W BW and Krensky, A M AM.. (1990) Molecular cloning and characterization of WP34, a phosphorylated human lymphocyte differentiation and activation antigen.. European journal of immunology, [PMID:2174784]
4.Jongstra-Bilen, J J, Young, A J AJ, Chong, R R and Jongstra, J J.. (1990) Human and mouse LSP1 genes code for highly conserved phosphoproteins.. Journal of immunology (Baltimore, Md. : 1950), (1):[PMID:2295815]
5.Howard, T T, Li, Y Y, Torres, M M, Guerrero, A A and Coates, T T.. (1994) The 47-kD protein increased in neutrophil actin dysfunction with 47- and 89-kD protein abnormalities is lymphocyte-specific protein.. Blood, (1):[PMID:8274738]
6.Wu, Yue Y and 6 more authors.. (2007) MAPKAPK2-mediated LSP1 phosphorylation and FMLP-induced neutrophil polarization.. Biochemical and biophysical research communications, (22):[PMID:17481585]
7.Mayya, Viveka V and 7 more authors.. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.. Science signaling, (18):[PMID:19690332]
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