| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab115021-10μl | 10μl | In stock | $66.90 | |
| Ab115021-50μl | 50μl | In stock | $189.90 | |
| Ab115021-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $299.90 | |
| Ab115021-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,809.90 |
Recombinant; Rabbit anti Human Mesothelin Antibody; WB; Unconjugated
| Product Name | Recombinant Mesothelin Antibody - Primary antibody, specific to Mesothelin, Rabbit IgG |
|---|---|
| Synonyms | CAK 1 antibody | CAK1 antibody | CAK1 antigen antibody | cleaved form antibody | Megakaryocyte potentiating factorantibody | Mesothelin antibody | Mesothelin isoform 1 precursorantibody | MPF antibody | Msln antibody | MSLN_HUMAN antibody | Pre pro megaka |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.8 mg/mL |
| Host species | Rabbit |
| Specificity | Mesothelin |
| Immunogen | A synthetic peptide derived from human Mesothelin (AA 550-570). |
| Positive Control | WB: HeLa lysates. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description | Rabbit anti Human Mesothelin Antibody, Recombinant, could be used for WB and so on. |
| Isotype | Rabbit IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant Mesothelin Antibody (Ab115021) - Western Blot
All lanes: Recombinant Mesothelin Antibody (Ab115021) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 69 kDa
Observed band size: 44, 69 kDa
Exposure time: 28.2 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000"> 1/500-1/1000 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0404159 | Certificate of Analysis | Apr 03, 2024 | Ab115021 |
| ZJ24F0404158 | Certificate of Analysis | Apr 03, 2024 | Ab115021 |
| 1. Kojima, T T and 6 more authors.. (1995) Molecular cloning and expression of megakaryocyte potentiating factor cDNA.. The Journal of biological chemistry, (15): [PMID:7665620] |
| 2. Yamaguchi, N N and 5 more authors.. (1994) A novel cytokine exhibiting megakaryocyte potentiating activity from a human pancreatic tumor cell line HPC-Y5.. The Journal of biological chemistry, (14): [PMID:8288629] |
| 3. Chang, K K and Pastan, I I.. (1996) Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers.. Proceedings of the National Academy of Sciences of the United States of America, (9): [PMID:8552591] |
| 4. Scholler, N N and 6 more authors.. (1999) Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma.. Proceedings of the National Academy of Sciences of the United States of America, (28): [PMID:10500211] |
| 5. Daniels, R J RJ and 10 more authors.. (2001) Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.. Human molecular genetics, (15): [PMID:11157797] |
| 6. Rump, Armin A and 6 more authors.. (2004) Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion.. The Journal of biological chemistry, (5): [PMID:14676194] |
| 7. Muminova, Zhanat E ZE, Strong, Theresa V TV and Shaw, Denise R DR.. (2004) Characterization of human mesothelin transcripts in ovarian and pancreatic cancer.. BMC cancer, (12): [PMID:15140265] |
| 8. Ho, Mitchell M and 6 more authors.. (2005) Humoral immune response to mesothelin in mesothelioma and ovarian cancer patients.. Clinical cancer research : an official journal of the American Association for Cancer Research, (15): [PMID:15897581] |
| 9. Onda, Masanori M and 6 more authors.. (2006) Megakaryocyte potentiation factor cleaved from mesothelin precursor is a useful tumor marker in the serum of patients with mesothelioma.. Clinical cancer research : an official journal of the American Association for Cancer Research, (15): [PMID:16857795] |
| 10. Ma, Jichun J, Tang, Wai Kwan WK, Esser, Lothar L, Pastan, Ira I and Xia, Di D.. (2012) Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.. The Journal of biological chemistry, (28): [PMID:22787150] |
