Recombinant Mesothelin Antibody - Primary antibody, specific to Mesothelin, Rabbit IgG

Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human Mesothelin Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab115021
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab115021-10μl
10μl
In stock
$66.90
Ab115021-50μl
50μl
In stock
$189.90
Ab115021-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab115021-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,809.90

Recombinant; Rabbit anti Human Mesothelin Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant Mesothelin Antibody - Primary antibody, specific to Mesothelin, Rabbit IgG
SynonymsCAK 1 antibody; CAK1 antibody; CAK1 antigen antibody; cleaved form antibody; Megakaryocyte potentiating factorantibody; Mesothelin antibody; Mesothelin isoform 1 precursorantibody; MPF antibody; Msln antibody; MSLN_HUMAN antibody; Pre pro megakaryocyte po
Specifications & PurityExactAb™, Validated, Recombinant, 0.8 mg/mL
Host speciesRabbit
SpecificityMesothelin
ImmunogenA synthetic peptide derived from human Mesothelin (AA 550-570).
Positive ControlWB: HeLa lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human Mesothelin Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function:
Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.8 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant Mesothelin Antibody (Ab115021) - Western Blot
All lanes: Recombinant Mesothelin Antibody (Ab115021) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 69 kDa
Observed band size: 44, 69 kDa
Exposure time: 28.2 s 

Associated Targets(Human)

MSLN Tbio Mesothelin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MSLN Tbio Mesothelin (0 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Application

ApplicationDilution info
WB

1/500-1/1000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404159Certificate of AnalysisApr 03, 2024 Ab115021
ZJ24F0404158Certificate of AnalysisApr 03, 2024 Ab115021

Related Documents

References

1. Kojima, T T and 6 more authors..  (1995)  Molecular cloning and expression of megakaryocyte potentiating factor cDNA..  The Journal of biological chemistry,    (15):   [PMID:7665620]
2. Yamaguchi, N N and 5 more authors..  (1994)  A novel cytokine exhibiting megakaryocyte potentiating activity from a human pancreatic tumor cell line HPC-Y5..  The Journal of biological chemistry,    (14):   [PMID:8288629]
3. Chang, K K and Pastan, I I..  (1996)  Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers..  Proceedings of the National Academy of Sciences of the United States of America,    (9):   [PMID:8552591]
4. Scholler, N N and 6 more authors..  (1999)  Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma..  Proceedings of the National Academy of Sciences of the United States of America,    (28):   [PMID:10500211]
5. Daniels, R J RJ and 10 more authors..  (2001)  Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16..  Human molecular genetics,    (15):   [PMID:11157797]
6. Rump, Armin A and 6 more authors..  (2004)  Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion..  The Journal of biological chemistry,    (5):   [PMID:14676194]
7. Muminova, Zhanat E ZE, Strong, Theresa V TV and Shaw, Denise R DR..  (2004)  Characterization of human mesothelin transcripts in ovarian and pancreatic cancer..  BMC cancer,    (12):   [PMID:15140265]
8. Ho, Mitchell M and 6 more authors..  (2005)  Humoral immune response to mesothelin in mesothelioma and ovarian cancer patients..  Clinical cancer research : an official journal of the American Association for Cancer Research,    (15):   [PMID:15897581]
9. Onda, Masanori M and 6 more authors..  (2006)  Megakaryocyte potentiation factor cleaved from mesothelin precursor is a useful tumor marker in the serum of patients with mesothelioma..  Clinical cancer research : an official journal of the American Association for Cancer Research,    (15):   [PMID:16857795]
10. Ma, Jichun J, Tang, Wai Kwan WK, Esser, Lothar L, Pastan, Ira I and Xia, Di D..  (2012)  Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights..  The Journal of biological chemistry,    (28):   [PMID:22787150]

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