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Recombinant MYL9 Antibody - Primary antibody, specific to MYL9, Rabbit IgG

Recombinant

Validated

ExactAb™

1.2 mg/mL

Application:

Features and benefits

Host species: Rabbit
Species reactivity(Reacts with): Human,Mouse,Rat
Isotype: Rabbit IgG
Conjugation: Unconjugated

Item Number

Ab116779

Grouped product items
SKU	Size	Availability	Price
Ab116779-10μl	10μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$69.90
Ab116779-50μl	50μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$199.90
Ab116779-100μl	100μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$309.90
Ab116779-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,799.90

Recombinant; Rabbit anti Human MYL9 Antibody; WB; Unconjugated

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Click to view target information: MYL9

Accession#:P24844 Gene ID:10398 MYL9

Basic Description

Product Name	Recombinant MYL9 Antibody - Primary antibody, specific to MYL9, Rabbit IgG
Synonyms	20 kDa myosin light chain \| LC20 \| MLC-2C \| Myosin regulatory light chain 2, smooth muscle isoform \| Myosin regulatory light chain 9 \| Myosin regulatory light chain MRLC1 \| Myosin RLC \| MYL9 \| LC20 \| MLC-2C \| MLC2 \| MMIHS4 \| MRLC1 \| MYRL2 \| 20 kDa myosin
Specifications & Purity	ExactAb™, Validated, Recombinant, 1.2 mg/mL
Host species	Rabbit
Specificity	MYL9
Immunogen	A synthetic peptide derived from human MYL9 (AA 60-80)
Positive Control	WB: A431, HeLa and U-2 OS cell lysates.
Conjugation	Unconjugated
Grade	ExactAb™, Recombinant, Validated
Product Description	Rabbit anti Human MYL9 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.

Product Properties

Isotype	Rabbit IgG
Light Chain Type	kappa
SDS-PAGE	150 kDa
Purification Method	Protein A purified
Form	Liquid
Concentration	1.2 mg/mL
Storage Temp	Store at -20°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Application

Dilution info

1/500-1/1000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot Number	Certificate Type	Date	Item
ZJ24F0708950	Certificate of Analysis	Jul 29, 2024	Ab116779
ZJ24F0708949	Certificate of Analysis	Jul 29, 2024	Ab116779

References

1. Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, Stavrides G, Almeida JP, Babbage AK, Bagguley CL, Bailey J, Barlow KF, Bates KN, Beard LM, Beare DM, Beasley OP, Bird CP, Blakey SE, Bridgeman AM, Brown AJ, Buck D, Burrill W, Butler AP, Carder C, Carter NP, Chapman JC, Clamp M, Clark G, Clark LN, Clark SY, Clee CM, Clegg S, Cobley VE, Collier RE, Connor R, Corby NR, Coulson A, Coville GJ, Deadman R, Dhami P, Dunn M, Ellington AG, Frankland JA, Fraser A, French L, Garner P, Grafham DV, Griffiths C, Griffiths MN, Gwilliam R, Hall RE, Hammond S, Harley JL, Heath PD, Ho S, Holden JL, Howden PJ, Huckle E, Hunt AR, Hunt SE, Jekosch K, Johnson CM, Johnson D, Kay MP, Kimberley AM, King A, Knights A, Laird GK, Lawlor S, Lehvaslaiho MH, Leversha M, Lloyd C, Lloyd DM, Lovell JD, Marsh VL, Martin SL, McConnachie LJ, McLay K, McMurray AA, Milne S, Mistry D, Moore MJ, Mullikin JC, Nickerson T, Oliver K, Parker A, Patel R, Pearce TA, Peck AI, Phillimore BJ, Prathalingam SR, Plumb RW, Ramsay H, Rice CM, Ross MT, Scott CE, Sehra HK, Shownkeen R, Sims S, Skuce CD, Smith ML, Soderlund C, Steward CA, Sulston JE, Swann M, Sycamore N, Taylor R, Tee L, Thomas DW, Thorpe A, Tracey A, Tromans AC, Vaudin M, Wall M, Wallis JM, Whitehead SL, Whittaker P, Willey DL, Williams L, Williams SA, Wilming L, Wray PW, Hubbard T, Durbin RM, Bentley DR, Beck S, Rogers J. (2001) The DNA sequence and comparative analysis of human chromosome 20.. Nature, 414 (6866): (865-71). [PMID:11780052] [10.1021/op500134e]
2. Kumar, C C CC, Mohan, S R SR, Zavodny, P J PJ, Narula, S K SK and Leibowitz, P J PJ.. (1989) Characterization and differential expression of human vascular smooth muscle myosin light chain 2 isoform in nonmuscle cells.. Biochemistry, (2): [PMID:2526655]
3. Iwasaki, T T, Murata-Hori, M M, Ishitobi, S S and Hosoya, H H.. (2001) Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells.. Cell structure and function, [PMID:11942626]
4. Tan, Ivan I, Yong, Jeffery J, Dong, Jing Ming JM, Lim, Louis L and Leung, Thomas T.. (2008) A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.. Cell, (3): [PMID:18854160]
5. Shoval, Yishay Y, Berissi, Hanna H, Kimchi, Adi A and Pietrokovski, Shmuel S.. (2011) New modularity of DAP-kinases: alternative splicing of the DRP-1 gene produces a ZIPk-like isoform.. PloS one, (8): [PMID:21408167]
6. Tan, Ivan I, Lai, Jesyin J, Yong, Jeffery J, Li, Sam F Y SF and Leung, Thomas T.. (2011) Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase.. FEBS letters, (6): [PMID:21457715]
7. Moreno, Carolina Araujo CA and 6 more authors.. (2018) Homozygous deletion in MYL9 expands the molecular basis of megacystis-microcolon-intestinal hypoperistalsis syndrome.. European journal of human genetics : EJHG, [PMID:29453416]
8. Kandler, Justin L and 5 more authors.. (2020) Compound heterozygous loss of function variants in MYL9 in a child with megacystis-microcolon-intestinal hypoperistalsis syndrome.. Molecular genetics & genomic medicine, [PMID:33031641]

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