Recombinant Nicastrin Antibody - Primary antibody, specific to NCSTN, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab118034
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab118034-10μl
10μl
In stock
$66.90
Ab118034-50μl
50μl
In stock
$189.90
Ab118034-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab118034-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

Recombinant; Rabbit anti Human Nicastrin Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant Nicastrin Antibody - Primary antibody, specific to NCSTN, Rabbit IgG
Synonymsanterior pharynx-defective 2 | APH2 | ATAG1874 | KIAA0253APH2 | NCSTN | Nicastrin | Anterior pharynx defective 2 antibody | APH 2 antibody | APH2 antibody | ATAG1874 antibody | KIAA0253 antibody | Ncstn antibody | NCT antibody | NICA_HUMAN antibody | Nica
Specifications & PurityExactAb™, Validated, Recombinant, 0.2 mg/mL
Host speciesRabbit
SpecificityNCSTN
ImmunogenA synthetic peptide derived from human Nicastrin (AA 696-709).
Positive ControlWB: HeLa, K562, Jurkat, Hep G2 and NIH/3T3 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human Nicastrin Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function:
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodAntigen affinity purified
FormLiquid
Concentration0.2 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant Nicastrin Antibody (Ab118034) - Western Blot
All lanes: Recombinant Nicastrin Antibody (Ab118034) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 78 kDa
Observed band size: 110-125 kDa
Exposure time: 52.9 s

Recombinant Nicastrin Antibody (Ab118034) - Western Blot
All lanes: Recombinant Nicastrin Antibody (Ab118034) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 78 kDa
Observed band size: 110-125 kDa
Exposure time: 52.9 s

Associated Targets(Human)

NCSTN Tbio Nicastrin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
WB1/500-1/1000

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1/500-1/1000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0202743Certificate of AnalysisFeb 06, 2024 Ab118034
ZJ24F0202744Certificate of AnalysisFeb 06, 2024 Ab118034

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