| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab118688-10μl | 10μl | In stock | $66.90 | |
| Ab118688-50μl | 50μl | In stock | $199.90 | |
| Ab118688-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,399.90 |
Recombinant; Rabbit anti Human NR2F2 Antibody; WB, IHC; Unconjugated
| Product Name | Recombinant NR2F2 Antibody - Primary antibody, specific to NR2F2, Rabbit IgG |
|---|---|
| Synonyms | Apolipoprotein A-I regulatory protein 1 antibody | Apolipoprotein AI regulatory protein 1 antibody | ARP-1 antibody | ARP1 antibody | COT2_HUMAN antibody | COUP TF2 antibody | COUP transcription factor 2 antibody | COUP transcription factor II antibody | |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.8 mg/mL |
| Host species | Rabbit |
| Specificity | NR2F2 |
| Immunogen | A synthetic peptide derived from human NR2F2 (AA 1-32) |
| Positive Control | WB: MCF7, HEK293, K562 and NIH/3T3 cell lysates. IHC: Human breast cancer tissue. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human NR2F2 Antibody, Recombinant, could be used for WB, IHC and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Antigen affinity purified |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant NR2F2 Antibody (Ab118688) - Western Blot
All lanes: Recombinant NR2F2 Antibody (Ab118688) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/50000 dilution
Predicted band size: 46 kDa
Observed band size: 42 kDa
Exposure time: 74.2 s
Recombinant NR2F2 Antibody (Ab118688) - IHC
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Recombinant NR2F2 Antibody (Ab118688). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000"> 1/500-1/1000 |
| IHC | 1/50 - 1/100 "> 1/50 - 1/100 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0303460 | Certificate of Analysis | Mar 20, 2024 | Ab118688 |
| ZJ24F0303459 | Certificate of Analysis | Mar 20, 2024 | Ab118688 |
| 1. Ladias JA, Karathanasis SK. (1991) Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily.. Science, 251 (4993): (561-5). [PMID:1899293] [10.1021/op500134e] |
| 2. Avram D, Ishmael JE, Nevrivy DJ, Peterson VJ, Lee SH, Dowell P, Leid M. (1999) Heterodimeric interactions between chicken ovalbumin upstream promoter-transcription factor family members ARP1 and ear2.. J Biol Chem, 274 (20): (14331-6). [PMID:10318855] [10.1021/op500134e] |
| 3. Kruse SW, Suino-Powell K, Zhou XE, Kretschman JE, Reynolds R, Vonrhein C, Xu Y, Wang L, Tsai SY, Tsai MJ, Xu HE. (2008) Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor.. PLoS Biol, 6 (9): (e227). [PMID:18798693] [10.1021/op500134e] |
| 4. Solt LA, Wang Y, Banerjee S, Hughes T, Kojetin DJ, Lundasen T, Shin Y, Liu J, Cameron MD, Noel R et al.. (2012) Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists.. Nature, 485 (7396): (62-8). [PMID:22460951] [10.1021/op500134e] |
| 5. Wang, L H LH, Ing, N H NH, Tsai, S Y SY, O'Malley, B W BW and Tsai, M J MJ.. (1991) The COUP-TFs compose a family of functionally related transcription factors.. Gene expression, [PMID:1820218] |
| 6. Chu, K K and Zingg, H H HH.. (1997) The nuclear orphan receptors COUP-TFII and Ear-2 act as silencers of the human oxytocin gene promoter.. Journal of molecular endocrinology, [PMID:9343308] |
| 7. Zody, Michael C MC and 68 more authors.. (2006) Analysis of the DNA sequence and duplication history of human chromosome 15.. Nature, (30): [PMID:16572171] |
| 8. Al Turki, Saeed S and 40 more authors.. (2014) Rare variants in NR2F2 cause congenital heart defects in humans.. American journal of human genetics, (3): [PMID:24702954] |
| 9. Bashamboo, Anu A and 17 more authors.. (2018) Loss of Function of the Nuclear Receptor NR2F2, Encoding COUP-TF2, Causes Testis Development and Cardiac Defects in 46,XX Children.. American journal of human genetics, (1): [PMID:29478779] |
