Recombinant NR2F2 Antibody - Primary antibody, specific to NR2F2, Rabbit IgG

Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human NR2F2 Antibody; WB, IHC; Unconjugated

  • Species reactivity(Reacts with): Human,Mouse
  • Isotype: Rabbit IgG
    Application:
  • IHC
  • WB
Item Number
Ab118688
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab118688-10μl
10μl
In stock
$66.90
Ab118688-50μl
50μl
In stock
$199.90
Ab118688-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,399.90

Recombinant; Rabbit anti Human NR2F2 Antibody; WB, IHC; Unconjugated

Basic Description

Product NameRecombinant NR2F2 Antibody - Primary antibody, specific to NR2F2, Rabbit IgG
SynonymsApolipoprotein A-I regulatory protein 1 antibody; Apolipoprotein AI regulatory protein 1 antibody; ARP-1 antibody; ARP1 antibody; COT2_HUMAN antibody; COUP TF2 antibody; COUP transcription factor 2 antibody; COUP transcription factor II antibody; COUP-TF
Specifications & PurityExactAb™, Validated, Recombinant, 0.8 mg/mL
Host speciesRabbit
SpecificityNR2F2
ImmunogenA synthetic peptide derived from human NR2F2 (AA 1-32)
Positive ControlWB: MCF7, HEK293, K562 and NIH/3T3 cell lysates. IHC: Human breast cancer tissue.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human NR2F2 Antibody, Recombinant, could be used for WB, IHC and so on.
Application:
WB: 1/500 - 1/1000
IHC: 1/50-1/100
Protein Function
Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodAntigen affinity purified
FormLiquid
Concentration0.8 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant NR2F2 Antibody (Ab118688) - Western Blot
All lanes: Recombinant NR2F2 Antibody (Ab118688) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/50000 dilution

Predicted band size: 46 kDa
Observed band size: 42 kDa
Exposure time: 74.2 s

Recombinant NR2F2 Antibody (Ab118688) - IHC
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Recombinant NR2F2 Antibody (Ab118688). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Associated Targets(Human)

NR2F2 Tchem COUP transcription factor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR2F2 Tchem COUP transcription factor 2 (234 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Application

ApplicationDilution info
WB

1/500-1/1000

IHC

1/50 - 1/100

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0303460Certificate of AnalysisMar 20, 2024 Ab118688
ZJ24F0303459Certificate of AnalysisMar 20, 2024 Ab118688

Related Documents

References

1. Ladias JA, Karathanasis SK.  (1991)  Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily..  Science,  251  (4993): (561-5).  [PMID:1899293]
2. Avram D, Ishmael JE, Nevrivy DJ, Peterson VJ, Lee SH, Dowell P, Leid M.  (1999)  Heterodimeric interactions between chicken ovalbumin upstream promoter-transcription factor family members ARP1 and ear2..  J Biol Chem,  274  (20): (14331-6).  [PMID:10318855]
3. Kruse SW, Suino-Powell K, Zhou XE, Kretschman JE, Reynolds R, Vonrhein C, Xu Y, Wang L, Tsai SY, Tsai MJ, Xu HE.  (2008)  Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor..  PLoS Biol,  (9): (e227).  [PMID:18798693]
4. Solt LA, Wang Y, Banerjee S, Hughes T, Kojetin DJ, Lundasen T, Shin Y, Liu J, Cameron MD, Noel R et al..  (2012)  Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists..  Nature,  485  (7396): (62-8).  [PMID:22460951]
5. Wang, L H LH, Ing, N H NH, Tsai, S Y SY, O'Malley, B W BW and Tsai, M J MJ..  (1991)  The COUP-TFs compose a family of functionally related transcription factors..  Gene expression,      [PMID:1820218]
6. Chu, K K and Zingg, H H HH..  (1997)  The nuclear orphan receptors COUP-TFII and Ear-2 act as silencers of the human oxytocin gene promoter..  Journal of molecular endocrinology,      [PMID:9343308]
7. Zody, Michael C MC and 68 more authors..  (2006)  Analysis of the DNA sequence and duplication history of human chromosome 15..  Nature,    (30):   [PMID:16572171]
8. Al Turki, Saeed S and 40 more authors..  (2014)  Rare variants in NR2F2 cause congenital heart defects in humans..  American journal of human genetics,    (3):   [PMID:24702954]
9. Bashamboo, Anu A and 17 more authors..  (2018)  Loss of Function of the Nuclear Receptor NR2F2, Encoding COUP-TF2, Causes Testis Development and Cardiac Defects in 46,XX Children..  American journal of human genetics,    (1):   [PMID:29478779]

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