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Recombinant p40 - DeltaNp63 Antibody - Primary antibody, specific to p40 - DeltaNp63, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • 0.03 mg/mL
Features and benefits
  • Short Overview:

    Recombinant (MyR1-P40); Rabbit anti Human p40 - DeltaNp63 Antibody; IHC; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Rabbit IgG
    Application:
  • IHC
Item Number
Ab119740
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab119740-10μl
10μl
In stock
$49.90
Ab119740-50μl
50μl
In stock
$159.90
Ab119740-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$239.90
Ab119740-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,199.90

Recombinant (MyR1-P40); Rabbit anti Human p40 - DeltaNp63 Antibody; IHC; Unconjugated

Basic Description

Product NameRecombinant p40 - DeltaNp63 Antibody - Primary antibody, specific to p40 - DeltaNp63, Rabbit IgG
Specifications & PurityExactAb™, Validated, Recombinant, 0.03 mg/mL
Host speciesRabbit
Specificityp40 - DeltaNp63
Positive ControlIHC: Human tonsil tissue.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human p40 - DeltaNp63 Antibody, Recombinant (MyR1-P40), could be used for IHC and so on.
Application
IHC: 1/100-1/200
Relevance
Differentiating between lung adenocarcinoma and squamous cell carcinoma is an important distinction with therapeutic implications. Although the most frequently recommended squamous marker p63 is extremely sensitive, it suffers from low specificity due to its reactivity in a substantial proportion of lung adenocarcinomas and other tumor types, particularly lymphomas. p40 is a relatively unknown marker that recognizes ?Np63-a p63 isoform suggested to be highly specific for squamous/basal cells. p40 is equivalent to p63 in sensitivity for squamous cell carcinoma, but it is markedly superior to p63 in specificity, which eliminates a potential pitfall of misinterpreting a p63-positive adenocarcinoma or unsuspected lymphoma as squamous cell carcinoma. These findings strongly support the routine use of p40 in place of p63 for the diagnosis of pulmonary squamous cell carcinoma.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.03 mg/mL
Storage TempStore at 2-8°C,Freeze prohibited
Shipped InWet ice
Stability And StorageStore at 2-8°C long term (36 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant p40 - DeltaNp63 Antibody (Ab119740) - IHC
Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling p40 - DeltaNp63 with Recombinant p40 - DeltaNp63 Antibody (Ab119740) at 1/200 dilution. The section was incubated with Ab119740 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Associated Targets

TP63 Tbio Tumor protein 63 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
IHC

1/100 - 1/200

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0505287Certificate of AnalysisMay 09, 2024 Ab119740
ZJ24F0505288Certificate of AnalysisMay 09, 2024 Ab119740

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