Recombinant PER2 Antibody - Primary antibody, specific to PER2, Rabbit IgG

Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human PER2 Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab121233
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab121233-10μl
10μl
In stock
$76.90
Ab121233-50μl
50μl
In stock
$229.90
Ab121233-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$399.90
Ab121233-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,999.90

Recombinant; Rabbit anti Human PER2 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant PER2 Antibody - Primary antibody, specific to PER2, Rabbit IgG
SynonymsFASPS; FASPS1; Circadian clock protein PERIOD 2 antibody; FASPS antibody; FASPS1 antibody; hPER 2 antibody; hPER2 antibody; KIAA0347 antibody; OTTHUMP00000164476 antibody; PER 2 antibody; PER2 antibody; PER2_HUMAN antibody; Period 2 antibody; Period 2 iso
Specifications & PurityExactAb™, Validated, Recombinant, 0.6 mg/mL
Host speciesRabbit
SpecificityPER2
ImmunogenA synthetic peptide derived from human PER2 (AA 50-100)
Positive ControlWB: A549 and Hep G2 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human PER2 Antibody, Recombinant, could be used for WB and so on.
Application
WB: 1/500-1/1000
Protein Function
Component of the circadian clock mechanism which is essential for generating circadian rhythms. Negative element in the circadian transcriptional loop. Influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. Negatively regulates CLOCK
NPAS2-BMAL1
BMAL2-induced transactivation.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.6 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant PER2 Antibody (Ab121233) - Western Blot
All lanes: Recombinant PER2 Antibody (Ab121233) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 137 kDa
Observed band size: 130 kDa
Exposure time: 10.0 s

Associated Targets(Human)

PER2 Tchem Period circadian protein homolog 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PER2 Tchem Period circadian protein homolog 2 (80 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PER2 Tchem CRY2/PER2 (55 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Application

ApplicationDilution info
WB

1/500-1/1000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0202824Certificate of AnalysisFeb 23, 2024 Ab121233
ZJ24F0202825Certificate of AnalysisFeb 23, 2024 Ab121233

Related Documents

References

1. Nagase, T T and 9 more authors..  (1997)  Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro..  DNA research : an international journal for rapid publication of reports on genes and genomes,    (28):   [PMID:9205841]
2. Shearman, L P LP, Zylka, M J MJ, Weaver, D R DR, Kolakowski, L F LF and Reppert, S M SM..  (1997)  Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei..  Neuron,      [PMID:9427249]
3. Camacho, F F and 9 more authors..  (2001)  Human casein kinase Idelta phosphorylation of human circadian clock proteins period 1 and 2..  FEBS letters,    (2):   [PMID:11165242]
4. Toh, K L KL and 7 more authors..  (2001)  An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome..  Science (New York, N.Y.),    (9):   [PMID:11232563]
5. Miyazaki, Koyomi K and 5 more authors..  (2004)  Phosphorylation of clock protein PER1 regulates its circadian degradation in normal human fibroblasts..  The Biochemical journal,    (15):   [PMID:14750904]
6. Hillier, Ladeana W LW and 121 more authors..  (2005)  Generation and annotation of the DNA sequences of human chromosomes 2 and 4..  Nature,    (7):   [PMID:15815621]
7. Sjöblom, Tobias T and 28 more authors..  (2006)  The consensus coding sequences of human breast and colorectal cancers..  Science (New York, N.Y.),    (13):   [PMID:16959974]
8. Miki, Takao T and 8 more authors..  (2012)  PML regulates PER2 nuclear localization and circadian function..  The EMBO journal,    (21):   [PMID:22274616]
9. Partch, Carrie L; Green, Carla B and Takahashi, Joseph S..  (2014)  Molecular architecture of the mammalian circadian clock..  Trends in cell biology,      [PMID:23916625]
10. Avitabile, Daniele D and 6 more authors..  (2014)  Nucleolar localization and circadian regulation of Per2S, a novel splicing variant of the Period 2 gene..  Cellular and molecular life sciences : CMLS,      [PMID:24202686]
11. Qu, Meng M, Duffy, Tomas T, Hirota, Tsuyoshi T and Kay, Steve A SA..  (2018)  Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks..  Proceedings of the National Academy of Sciences of the United States of America,    (26):   [PMID:30530698]

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