| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab122912-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 | |
| Ab122912-50μl | 50μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $199.90 | |
| Ab122912-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $319.90 | |
| Ab122912-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,499.90 |
Recombinant; Rabbit anti Human PR3 Antibody; WB; Unconjugated
| Product Name | Recombinant PR3 Antibody |
|---|---|
| Synonyms | P29 | PR3 | PR-3 | CANCA | ACPA | AGP7 | AGP7PR3 | azurophil granule protein 7 | C-ANCA | EC 3.4.21 | EC 3.4.21.76 | Leukocyte proteinase 3 | MBN | MBT | Myeloblastin | Neutrophil proteinase 4 | NP4 | NP-4 | P29C-ANCA antigen | PR-3CANCA | Proteinase 3 | |
| Specifications & Purity | Recombinant, ExactAb™, Validated, See COA |
| Biochemical and Physiological Mechanisms | Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. |
| Host species | Rabbit |
| Specificity | PR3 |
| Immunogen | A synthetic peptide derived from human PRTN3 (AA 64-100) |
| Positive Control | WB: HL60 and THP-1 cell lysates. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human PR3 Antibody, Recombinant, could be used for WB and so on.
|
| Isotype | Rabbit IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant PR3 Antibody (Ab122912) - Western Blot
All lanes: Recombinant PR3 Antibody (Ab122912) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 28 kDa
Observed band size: 29 kDa
The expression profile and molecular weight observed, which is due to glycosylation.
Exposure time: 35.1 s
Recombinant PR3 Antibody (Ab122912) - Western Blot
All lanes: Recombinant PR3 Antibody (Ab122912) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 28 kDa
Observed band size: 29 kDa
The expression profile and molecular weight observed, which is due to glycosylation.
Exposure time: 35.0 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/1000 - 1/2000"> 1/1000 - 1/2000 |
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