Recombinant protein (Active)(test) - Recombinant protein, ≥95%, high purityused for Sandwich ELISA,Cell Culture,Mass Spectrometry various applications, CAS No.CAS1111111-111-1, Agonist of 5-HT 1A receptor;Agonist of 5-HT 1B receptor;Agonist of 5-HT 1D receptor;Agonist of 5-ht 1e receptor;Agonist of 5-HT 1F receptor;Agonist of 5-HT 2A receptor;Agonist of 5-HT 2B receptor;Agonist of 5-HT 2C receptor;Agonist of 5-HT 5A receptor;Ago

  • 中文浓度
Features and benefits
  • Expression System: HEK293
  • Accession #: P01375
  • Protein Tag: 废弃10His + B2M+ JD,N-terminus + Myc,C-terminus
  • Bioactivity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependant Killing/apoptosis of L-929 cells is 0.71ng/mL corresponding to a Specific Activity of 1.41 x 106 IU/mg.
  • Endotoxin Concentration: < 0.005 Eu/µg
  • Application: Sandwich ELISA,Cell Culture,Mass Spectrometry
Item Number
R419388
Grouped product items
SKUSizeAvailabilityPrice Qty
R419388-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
R419388-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$7,000.90
R419388-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$10,000.90

Recombinant human TNF alpha protein

View related series
TNF Receptor

Basic Description

Product NameRecombinant protein (Active)(test) - Recombinant protein, ≥95%, high purityused for Sandwich ELISA,Cell Culture,Mass Spectrometry various applications, CAS No.CAS1111111-111-1
Synonymsmethanol | methyl alcohol | 67-56-1 | wood alcohol | carbinol | Wood naphtha | Methylol | Methyl hydroxide | Methylalkohol | Monohydroxymethane | Alcohol, methyl | Alcool methylique | MeOH | Methyl hydrate | CH3OH | Metanolo | Alcool metilico | Metylowy alkohol | Freers Elm Arrester | Surflo-
Product Description

This is Description in english

Our Abpromise guarantee covers the use of ab259410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Sandwich ELISA

    Cell Culture

    Functional Studies

    Mass Spectrometry

    HPLC

    SDS-PAGE

Specifications & Purity中文浓度
Biochemical and Physiological Mechanisms英文生化和生理学机理
Purity≥95%
BioactivityFully biologically active when compared to standard. The ED50 as determined by the dose-dependant Killing/apoptosis of L-929 cells is 0.71ng/mL corresponding to a Specific Activity of 1.41 x 106 IU/mg.
Endotoxin Concentration< 0.005 Eu/µg
Expression SystemHEK293
SpeciesHuman
Amino Acids77 to 233
Matched Pairs配对抗体(Matched Pairs)
SequenceVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVV PSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSP CQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQV YFGIIAL
Protein Tag废弃10His + B2M+ JD,N-terminus + Myc,C-terminus
N-terminal SequenceN-末端序列
Protein LengthFull length protein
Carrier Free Carrier Free
Animal Free Animal Free
ConjugationAlexa Fluor® 647
ModificationsThe soluble form derives from the membrane form by proteolytic processing. The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1. O-glycosyla
Accession #P01375
Source来源
Predicted molecular weight17 kDa
SDS-PAGESDS-PAGE
Action TypeAGONIST
Mechanism of actionAgonist of 5-HT 1A receptor;Agonist of 5-HT 1B receptor;Agonist of 5-HT 1D receptor;Agonist of 5-ht 1e receptor;Agonist of 5-HT 1F receptor;Agonist of 5-HT 2A receptor;Agonist of 5-HT 2B receptor;Agonist of 5-HT 2C receptor;Agonist of 5-HT 5A receptor;Ago
NoteNote

Product Properties

ALogPALogP
hba_count30
HBD Count50
Rotatable Bond80
NacresNACRES
Extinction coefficientextinction coefficient
Reactive groupreactive group
ReactivityReactivity

Images

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Associated Targets(Human)

HTR1B Tclin 5-hydroxytryptamine receptor 1B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR5A Tchem 5-hydroxytryptamine receptor 5A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2A Tclin 5-hydroxytryptamine receptor 2A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1E Tchem 5-hydroxytryptamine receptor 1E (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR7 Tclin 5-hydroxytryptamine receptor 7 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1D Tclin 5-hydroxytryptamine receptor 1D (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1F Tclin 5-hydroxytryptamine receptor 1F (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2C Tclin 5-hydroxytryptamine receptor 2C (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1A Tclin 5-hydroxytryptamine receptor 1A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2B Tclin 5-hydroxytryptamine receptor 2B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B4 Tbio UDP-glucuronosyltransferase 2B4 (139 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UGT2B10 Tbio UDP-glucuronosyltransferase 2B10 (42 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus cereus (7522 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Tetrahymena pyriformis (68 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lithobates pipiens (29 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Colletotrichum gloeosporioides (560 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Product Specifications

ApplicationSandwich ELISA,Cell Culture,Mass Spectrometry
Form物理性状
Concentration中文浓度
ReconstitutionReconstitute with Phosphate Buffered Saline.Reconstituted protein stable at -80C for 12 months or 4C for 1 week. Lyophilized contents may appear as either a translucent film or a white powder. This variance does not affect the quality of the product.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Stability And StorageShipped at Room Temperature. Store at Room Temperature. Information available upon request. This product is an active protein and may elicit a biological response in vivo, handle with caution.
CASCAS1111111-111-1
Enzyme Commission NumberEnzyme Commission Number
Unit definitionUnit definition

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

DMSO(mg / mL) Max SolubilityDMSO(mg / mL) Max Solubility
DMSO(mM) Max SolubilityDMSO(mM) Max Solubility
Water(mg / mL) Max SolubilityWater(mg / mL) Max Solubility
Water(mM) Max SolubilityWater(mM) Max Solubility
Freezing Point(°C)Freezing point(°C)英文页面1
Refractive IndexRefractive index英文页面1
Specific Rotation[α]Specific rotation[α]英文页面1
Flash Point(°F)Flash Point(°F)英文页面1
Flash Point(°C)Flash Point(°C)英文页面1
Boil Point(°C)Boil point(°C)英文页面1
Melt Point(°C)Melt point(°C)英文页面1

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS09,   GHS02
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

WGK Germany WGK Germany英文页面1
RTECS RTECS英文页面1
Reaxy-Rn Reaxy-Rn英文页面1
Reaxys-RN_link_address Reaxys-RN_link_address英文页面1
Class 6.1
Merck Index Merck Index英文页面1
RIDADR RIDADR英文页面1

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Solution Calculators