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Recombinant PTP1B Antibody - Primary antibody, specific to PTP1B, Rabbit IgG

    Application:
  • Flow Cytometry
  • IF/ICC
  • IHC
  • WB
Features and benefits
  • Host species: Mouse
  • Species reactivity(Reacts with): Dog,Human,Monkey,Rat
  • Isotype: Mouse IgG2a
  • Clone Number: OTI1D10
  • Conjugation: Unconjugated
Item Number
Ab123873
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab123873-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab123873-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$209.90
Ab123873-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$339.90
Ab123873-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,999.90
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mAb (OTI1D10); Mouse anti Human PTP1B Antibody; WB, IHC, IF/ICC, Flow Cytometry; Unconjugated

View related series
Click to view target information: PTPN1
Accession#:P18031 Gene ID:5770 PTP1B PTPN1

Basic Description

Product NameRecombinant PTP1B Antibody - Primary antibody, specific to PTP1B, Rabbit IgG
SynonymsPTP1B antibody | Non receptor tyrosine phosphatase 1 antibody | Protein phosphotyrosylphosphatase 1B antibody | Protein tyrosine phosphatase 1B antibody | Protein tyrosine phosphatase non receptor type 1 antibody | Protein tyrosine phosphatase placental a
Specifications & PurityKO Validation, ExactAb™, Validated, See COA
Biochemical and Physiological MechanismsTyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-s
Host speciesMouse
SpecificityPTP1B
ImmunogenRecombinant full length protein of human PTP1B.
Positive ControlWB: Hep G2 and HeLa cell lysates. IHC: Human colon, lymph node, lymphoma tissues. IF/ICC: COS7 cells transiently transfected with pCMV6-ENTRY PTPN1. Flow Cytometry: HEK293T cells transfected with pCMV6-ENTRY PTPN1.
ConjugationUnconjugated
GradeExactAb™, KO Validation, Validated
Product Description

Mouse anti Human PTP1B Antibody, Monoclonal (OTI1D10), could be used for WB, IHC, IF/ICC, Flow Cytometry and so on.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
ConcentrationSee COA
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

PTP1B Mouse mAb (Ab123873) - Western Blot
All lanes: PTP1B Mouse mAb (Ab123873) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 50 kDa
Observed band size: 49 kDa
Exposure time: 33.7 s

PTP1B Mouse mAb (Ab123873) - IHC
Immunohistochemical staining of paraffinembedded Human lymph node tissue within the normal limits using PTP1B Mouse mAb (Ab123873). (Heat-induced epitope retrieval by 10 mM citric buffer, pH 6.0, 100°C for 10 min)

PTP1B Mouse mAb (Ab123873) - IHC
Immunohistochemical staining of paraffinembedded Human colon tissue within the normal limits using PTP1B Mouse mAb (Ab123873). (Heat-induced epitope retrieval by 10 mM citric buffer, pH 6.0, 100°C for 10 min)

PTP1B Mouse mAb (Ab123873) - IHC
Immunohistochemical staining of paraffinembedded Human lymphoma tissue using PTP1B Mouse mAb (Ab123873). (Heatinduced epitope retrieval by 10 mM citric buffer, pH 6.0, 100°C for 10 min)

PTP1B Mouse mAb (Ab123873) - IF/ICC
PTP1B Mouse mAb (Ab123873) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PTPN1.

PTP1B Mouse mAb (Ab123873) - Flow
HEK293T cells transfected with either pCMV6-ENTRY PTPN1 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by PTP1B Mouse mAb (Ab123873), and then analyzed by flow cytometry.

Associated Targets(Human)

PTPN1 Tchem Tyrosine-protein phosphatase non-receptor type 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
WB1/500-1/2000

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1/500-1/2000

Flow Cytometry1/100

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1/100

IF/ICC1/100

">

1/100

IHC1/150

">

1/150

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

 SDS

 Specification Sheet

References

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50. Zhang X, He Y, Liu S, Yu Z, Jiang ZX, Yang Z, Dong Y, Nabinger SC, Wu L, Gunawan AM, Wang L, Chan RJ, Zhang ZY..  (2010)  Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2)..  J Med Chem,  53  (6): (2482-2493).  [PMID:20170098] [10.1021/jm901645u]
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52. Kumar A, Maurya RA, Sharma S, Ahmad P, Singh AB, Bhatia G, Srivastava AK..  (2009)  Pyranocoumarins: a new class of anti-hyperglycemic and anti-dyslipidemic agents..  Bioorg Med Chem Lett,  19  (22): (6447-6451).  [PMID:19811915] [10.1016/j.bmcl.2009.09.031]
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