Recombinant Reelin Antibody - Primary antibody, specific to Reelin, Rabbit IgG

Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human Reelin Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human,Rat
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab124937
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab124937-10μl
10μl
In stock
$79.90
Ab124937-50μl
50μl
In stock
$239.90
Ab124937-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$409.90
Ab124937-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,299.90

Recombinant; Rabbit anti Human Reelin Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant Reelin Antibody - Primary antibody, specific to Reelin, Rabbit IgG
SynonymsETL7 | LIS2 | PRO1598 | EC 3.4.21 | EC 3.4.21.- | Reeler | Reelin | RELN | RL | RLPRO1598 | LIS2 antibody | PRO1598 antibody | Reeler antibody | Reelin antibody | RELN antibody | RELN_HUMAN antibody | RL antibody | EC 3.4.21.-
Specifications & PurityExactAb™, Validated, Recombinant, 1.1 mg/mL
Host speciesRabbit
SpecificityReelin
ImmunogenA synthetic peptide derived from human Reelin (AA 3240-3300).
Positive ControlWB: Hep G2 and C6 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human Reelin Antibody, Recombinant, could be used for WB and so on.
Application
WB: 1/500-1/2000
Protein Function 
Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration1.1 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant Reelin Antibody (Ab124937) - Western Blot
All lanes: Recombinant Reelin Antibody (Ab124937) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 388 kDa
Observed band size: 100, 388 kDa
Exposure time: 100.0 s

Associated Targets(Human)

RELN Tbio Reelin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/2000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0404690Certificate of AnalysisApr 19, 2024 Ab124937
ZJ24F0404689Certificate of AnalysisApr 19, 2024 Ab124937

Related Documents

References

1. Scherer SW, Cheung J, MacDonald JR, Osborne LR, Nakabayashi K, Herbrick JA, Carson AR, Parker-Katiraee L, Skaug J, Khaja R et al..  (2003)  Human chromosome 7: DNA sequence and biology..  Science,  300  (5620): (767-72).  [PMID:12690205]
2. DeSilva, U U and 6 more authors..  (1997)  The human reelin gene: isolation, sequencing, and mapping on chromosome 7..  Genome research,      [PMID:9049633]
3. Impagnatiello, F F and 13 more authors..  (1998)  A decrease of reelin expression as a putative vulnerability factor in schizophrenia..  Proceedings of the National Academy of Sciences of the United States of America,    (22):   [PMID:9861036]
4. Lambert de Rouvroit, C C, Bernier, B B, Royaux, I I, de Bergeyck, V V and Goffinet, A M AM..  (1999)  Evolutionarily conserved, alternative splicing of reelin during brain development..  Experimental neurology,      [PMID:10328932]
5. Hong, S E SE and 7 more authors..  (2000)  Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations..  Nature genetics,      [PMID:10973257]
6. Persico, A M AM and 22 more authors..  (2001)  Reelin gene alleles and haplotypes as a factor predisposing to autistic disorder..  Molecular psychiatry,      [PMID:11317216]
7. Hillier, Ladeana W LW and 106 more authors..  (2003)  The DNA sequence of human chromosome 7..  Nature,    (10):   [PMID:12853948]
8. Dazzo, Emanuela E and 22 more authors..  (2015)  Heterozygous reelin mutations cause autosomal-dominant lateral temporal epilepsy..  American journal of human genetics,    (4):   [PMID:26046367]

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