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Recombinant RIG-I/DDX58 Antibody - Primary antibody, specific to RIGI, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • 3.0 mg/mL
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human RIG-I Antibody; WB; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Rabbit IgG
    Application:
  • WB
Item Number
Ab125359
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab125359-10μl
10μl
In stock
$66.90
Ab125359-50μl
50μl
In stock
$189.90
Ab125359-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab125359-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

Recombinant; Rabbit anti Human RIG-I Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant RIG-I/DDX58 Antibody - Primary antibody, specific to RIGI, Rabbit IgG
SynonymsDdx58 antibody; DDX58_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 58 antibody; DEAD (Asp Glu Ala Asp/His) box polypeptideantibody; DEAD box protein 58 antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide RIG1 antibody; DKFZp434J1111 antibody;
Specifications & PurityExactAb™, Validated, Recombinant, 3.0 mg/mL
Host speciesRabbit
SpecificityRIGI
ImmunogenA synthetic peptide derived from human DDX58 (AA 220-450)
Positive ControlWB: Jurkat, A549, HeLa and HEK293 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human RIG-I Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function
Involved in innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, triggers a transduction cascade involving MAVS/IPS1, which results in the activation of NF-kappa-B, IRF3 and IRF7 and the induction of the expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). Detects dsRNA produced from non-self dsDNA by RNA polymerase III, such as Epstein-Barr virus-encoded RNAs (EBERs). Essential for the production of interferons in response to RNA viruses including paramyxoviruses, influenza viruses, Japanese encephalitis virus and HCV.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration3.0 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant RIG-I/DDX58 Antibody (Ab125359) - Western Blot
All lanes: Recombinant RIG-I/DDX58 Antibody (Ab125359) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/40000 dilution

Predicted band size: 107 kDa
Observed band size: 112 kDa
Exposure time: 50.0 s

Associated Targets

DDX58 Tbio Probable ATP-dependent RNA helicase DDX58 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/1000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0202936Certificate of AnalysisMar 01, 2024 Ab125359
ZJ24F0202937Certificate of AnalysisMar 01, 2024 Ab125359

Related Documents

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