Recombinant SFRP1 Antibody - Primary antibody, specific to SFRP1, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab127297
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab127297-10μl
10μl
In stock
$66.90
Ab127297-50μl
50μl
In stock
$199.90
Ab127297-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$289.90
Ab127297-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,399.90

Recombinant; Rabbit anti Human SFRP1 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant SFRP1 Antibody - Primary antibody, specific to SFRP1, Rabbit IgG
SynonymsFrizzled related protein 1 antibody | FRP 1 antibody | FRP antibody | FRP-1 antibody | FRP1 antibody | FrzA antibody | SARP 2 antibody | SARP-2 antibody | SARP2 antibody | Secreted apoptosis related protein 2antibody | Secreted apoptosis-related protein 2
Specifications & PurityExactAb™, Validated, Recombinant, 0.5 mg/mL
Host speciesRabbit
SpecificitySFRP1
ImmunogenA synthetic peptide derived from human SFRP1 (AA 20-84).
Positive ControlWB: A375, A549, SK-N-SH and C6 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human SFRP1 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.5 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant SFRP1 Antibody (Ab127297) - Western Blot
All lanes: Recombinant SFRP1 Antibody (Ab127297) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 35 kDa
Observed band size: 35 kDa
Exposure time: 18.1 s


Associated Targets(Human)

SFRP1 Tchem Secreted frizzled-related protein 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
WB1/500-1/1000

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1/500-1/1000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0202979Certificate of AnalysisFeb 29, 2024 Ab127297
ZJ24F0202978Certificate of AnalysisFeb 29, 2024 Ab127297

Related Documents

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