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SIRT1 Antibody - Primary antibody, specific to SIRT1, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • Lot by Lot
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human SIRT1 Antibody; WB, IHC, IF/ICC, IP; Unconjugated

  • Species reactivity(Reacts with): Human
  • Isotype: Rabbit IgG
    Application:
  • ICC/IF
  • IHC
  • IP
  • WB
Item Number
Ab127656
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab127656-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab127656-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$169.90
Ab127656-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$249.90
Ab127656-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90

Recombinant; Rabbit anti Human SIRT1 Antibody; WB, IHC, IF/ICC, IP; Unconjugated

Basic Description

Product NameSIRT1 Antibody - Primary antibody, specific to SIRT1, Rabbit IgG
Synonyms2.3.1.- | EC 2.3.1.286 | hSIR2 | hSIRT1 | NAD-dependent protein deacylase sirtuin-1 | Regulatory protein SIR2 homolog 1 | SIR2-like protein 1 | EC 3.5.1 | S. cerevisiae, homolog) 1 | SIR2alpha | SIR2L1 | SIR2-like protein 1 | SIRT1 | Sirtuin 1 | SIR2 | 75
Specifications & PurityExactAb™, Validated, Recombinant, Lot by Lot
Host speciesRabbit
SpecificitySIRT1
ImmunogenA synthetic peptide derived from human SIRT1(AA 700-740)
Positive ControlWB: A549, HeLa, K562, MCF7, Jurkat and Hep G2 cell lysates. IHC: Rat stomach, Human pituitary tumor, Human colon, Human placenta, Mouse lung, Human kidney tissue. IF/ICC: HeLa cells. IP: HeLa lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human SIRT1 Antibody, Recombinant, could be used for WB, IHC, IF/ICC, IP and so on.
Application:
WB: 1/500-1/2000
IHC: 1/50-1/200
IF/ICC: 1/50-1/200
IP: 1/30

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Associated Targets

SIRT1 Tchem NAD-dependent protein deacetylase sirtuin-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/2000

IF/ICC

1/50 - 1/200

IHC

1/50-1/200

IP

1/30

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0708453Certificate of AnalysisJul 17, 2024 Ab127656
ZJ24F0708452Certificate of AnalysisJul 17, 2024 Ab127656

Related Documents

References

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49. Damonte P, Sociali G, Parenti MD, Soncini D, Bauer I, Boero S, Grozio A, Holtey MV, Piacente F, Becherini P, Sanguineti R, Salis A, Damonte G, Cea M, Murone M, Poggi A, Nencioni A, Del Rio A, Bruzzone S..  (2017)  SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects..  Bioorg Med Chem,  25  (20): (5849-5858).  [PMID:28958848]
50. Atobe M, Yamakawa N, Wada Y, Goto T, Kawanishi M, Ito T, Saito M, Takeda M, Tabata T, Arai H..  (2017)  A series of novel indazole derivatives of Sirt 1 activator as osteogenic regulators..  Bioorg Med Chem Lett,  27  (21): (4828-4831).  [PMID:28988762]
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53. Monaldi D, Rotili D, Lancelot J, Marek M, Wössner N, Lucidi A, Tomaselli D, Ramos-Morales E, Romier C, Pierce RJ, Mai A, Jung M..  (2019)  Structure-Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from Schistosoma mansoni (SmSirt2)..  J Med Chem,  62  (19): (8733-8759).  [PMID:31496251]
54. Bouchet S, Linot C, Ruzic D, Agbaba D, Fouchaq B, Roche J, Nikolic K, Blanquart C, Bertrand P..  (2019)  Extending Cross Metathesis To Identify Selective HDAC Inhibitors: Synthesis, Biological Activities, and Modeling..  ACS Med Chem Lett,  10  (6): (863-868).  [PMID:31223439]
55. Valente S, Mellini P, Spallotta F, Carafa V, Nebbioso A, Polletta L, Carnevale I, Saladini S, Trisciuoglio D, Gabellini C, Tardugno M, Zwergel C, Cencioni C, Atlante S, Moniot S, Steegborn C, Budriesi R, Tafani M, Del Bufalo D, Altucci L, Gaetano C, Mai A..  (2016)  1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells..  J Med Chem,  59  (4): (1471-1491).  [PMID:26689352]
56. Gromek SM, deMayo JA, Maxwell AT, West AM, Pavlik CM, Zhao Z, Li J, Wiemer AJ, Zweifach A, Balunas MJ..  (2016)  Synthesis and biological evaluation of santacruzamate A analogues for anti-proliferative and immunomodulatory activity..  Bioorg Med Chem,  24  (21): (5183-5196).  [PMID:27614919]
57. Farooqi AS, Hong JY, Cao J, Lu X, Price IR, Zhao Q, Kosciuk T, Yang M, Bai JJ, Lin H..  (2019)  Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model..  J Med Chem,  62  (8): (4131-4141).  [PMID:30986062]
58. Seifert T, Malo M, Kokkola T, Stéen EJL, Meinander K, Wallén EAA, Jarho EM, Luthman K..  (2020)  A scaffold replacement approach towards new sirtuin 2 inhibitors..  Bioorg Med Chem,  28  (2): (115231-115231).  [PMID:31848116]
59. Sun W, Chen X, Huang S, Li W, Tian C, Yang S, Li L..  (2020)  Discovery of 5-(4-methylpiperazin-1-yl)-2-nitroaniline derivatives as a new class of SIRT6 inhibitors..  Bioorg Med Chem Lett,  30  (16): (127215-127215).  [PMID:32631504]
60. Chen X, Sun W, Huang S, Zhang H, Lin G, Li H, Qiao J, Li L, Yang S..  (2020)  Discovery of Potent Small-Molecule SIRT6 Activators: Structure-Activity Relationship and Anti-Pancreatic Ductal Adenocarcinoma Activity..  J Med Chem,  63  (18): (10474-10495).  [PMID:32787077]
61. Wang XX,Wan RZ,Liu ZP.  (2018)  Recent advances in the discovery of potent and selective HDAC6 inhibitors..  Eur J Med Chem,  143  (1406-1418).  [PMID:29133060]
62. Yang LL,Wang HL,Yan YH,Liu S,Yu ZJ,Huang MY,Luo Y,Zheng X,Yu Y,Li GB.  (2020)  Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery..  Eur J Med Chem,  192  (112201-112201).  [PMID:32163813]
63. Yagci S,Gozelle M,Kaya SG,Ozkan Y,Aksel AB,Bakar-Ates F,Dundar Y,Eren G.  (2021)  Hit-to-lead optimization on aryloxybenzamide derivative virtual screening hit against SIRT..  Bioorg Med Chem,  30  (115961-115961).  [PMID:33360574]
64. and Frye, R A RA..  (1999)  Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity..  Biochemical and biophysical research communications,    (24):   [PMID:10381378]
65. Vaziri, H H and 7 more authors..  (2001)  hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase..  Cell,    (19):   [PMID:11672523]
66. Langley, Emma E and 7 more authors..  (2002)  Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence..  The EMBO journal,    (15):   [PMID:12006491]
67. Bitterman, Kevin J KJ, Anderson, Rozalyn M RM, Cohen, Haim Y HY, Latorre-Esteves, Magda M and Sinclair, David A DA..  (2002)  Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1..  The Journal of biological chemistry,    (22):   [PMID:12297502]
68. Takata, Takehiko T and Ishikawa, Fuyuki F..  (2003)  Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression..  Biochemical and biophysical research communications,    (31):   [PMID:12535671]
69. Howitz, Konrad T KT and 11 more authors..  (2003)  Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan..  Nature,    (11):   [PMID:12939617]
70. Brunet, Anne A and 16 more authors..  (2004)  Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase..  Science (New York, N.Y.),    (26):   [PMID:14976264]
71. Motta, Maria Carla MC and 8 more authors..  (2004)  Mammalian SIRT1 represses forkhead transcription factors..  Cell,    (20):   [PMID:14980222]
72. van der Horst, Armando A and 5 more authors..  (2004)  FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)..  The Journal of biological chemistry,    (9):   [PMID:15126506]
73. Deloukas, P P and 135 more authors..  (2004)  The DNA sequence and comparative analysis of human chromosome 10..  Nature,    (27):   [PMID:15164054]
74. Cohen, Haim Y HY and 9 more authors..  (2004)  Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase..  Science (New York, N.Y.),    (16):   [PMID:15205477]
75. Vaquero, Alejandro A and 5 more authors..  (2004)  Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin..  Molecular cell,    (8):   [PMID:15469825]
76. Kuzmichev, Andrei A and 10 more authors..  (2005)  Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation..  Proceedings of the National Academy of Sciences of the United States of America,    (8):   [PMID:15684044]
77. Yang, Yonghua Y, Hou, Huayan H, Haller, Edward M EM, Nicosia, Santo V SV and Bai, Wenlong W..  (2005)  Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation..  The EMBO journal,    (9):   [PMID:15692560]
78. Pagans, Sara S and 13 more authors..  (2005)  SIRT1 regulates HIV transcription via Tat deacetylation..  PLoS biology,      [PMID:15719057]
79. Michishita, Eriko E, Park, Jean Y JY, Burneskis, Jenna M JM, Barrett, J Carl JC and Horikawa, Izumi I..  (2005)  Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins..  Molecular biology of the cell,      [PMID:16079181]
80. Zhao, Xuan X, Sternsdorf, Thomas T, Bolger, Timothy A TA, Evans, Ronald M RM and Yao, Tso-Pang TP..  (2005)  Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications..  Molecular and cellular biology,      [PMID:16166628]
81. Heltweg, Birgit B and 10 more authors..  (2006)  Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes..  Cancer research,    (15):   [PMID:16618762]
82. Wang, Chuangui C and 10 more authors..  (2006)  Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage..  Nature cell biology,      [PMID:16892051]
83. Beausoleil, Sean A SA, Villén, Judit J, Gerber, Scott A SA, Rush, John J and Gygi, Steven P SP..  (2006)  A probability-based approach for high-throughput protein phosphorylation analysis and site localization..  Nature biotechnology,      [PMID:16964243]
84. Dai, Jin Ming JM, Wang, Zhi Yan ZY, Sun, Dao Chun DC, Lin, Ru Xian RX and Wang, Sheng Qi SQ..  (2007)  SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity..  Journal of cellular physiology,      [PMID:16998810]
85. Stankovic-Valentin, Nicolas N and 7 more authors..  (2007)  An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity..  Molecular and cellular biology,      [PMID:17283066]
86. Pedersen, Thomas A TA and 7 more authors..  (2007)  Distinct C/EBPalpha motifs regulate lipogenic and gluconeogenic gene expression in vivo..  The EMBO journal,    (21):   [PMID:17290224]
87. Jeong, Jaemin J and 8 more authors..  (2007)  SIRT1 promotes DNA repair activity and deacetylation of Ku70..  Experimental & molecular medicine,    (28):   [PMID:17334224]
88. Dai, Yan Y and 5 more authors..  (2007)  Sirtuin 1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor..  Molecular endocrinology (Baltimore, Md.),      [PMID:17505061]
89. Yuan, Zhigang Z, Zhang, Xiaohong X, Sengupta, Nilanjan N, Lane, William S WS and Seto, Edward E..  (2007)  SIRT1 regulates the function of the Nijmegen breakage syndrome protein..  Molecular cell,    (6):   [PMID:17612497]
90. Wong, Sharon S and Weber, Jason D JD..  (2007)  Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1..  The Biochemical journal,    (1):   [PMID:17620057]
91. Ghosh, Hiyaa S HS, Spencer, James V JV, Ng, Bobby B, McBurney, Michael W MW and Robbins, Paul D PD..  (2007)  Sirt1 interacts with transducin-like enhancer of split-1 to inhibit nuclear factor kappaB-mediated transcription..  The Biochemical journal,    (15):   [PMID:17680780]
92. Li, Xiaoling X and 5 more authors..  (2007)  SIRT1 deacetylates and positively regulates the nuclear receptor LXR..  Molecular cell,    (12):   [PMID:17936707]
93. Kim, Eun-Joo EJ, Kho, Jeong-Hoon JH, Kang, Moo-Rim MR and Um, Soo-Jong SJ..  (2007)  Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity..  Molecular cell,    (26):   [PMID:17964266]
94. Vaquero, Alejandro A and 5 more authors..  (2007)  SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation..  Nature,    (15):   [PMID:18004385]
95. Li, Kai K and 9 more authors..  (2008)  Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation..  The Journal of biological chemistry,    (21):   [PMID:18203716]
96. Kim, Ja-Eun JE, Chen, Junjie J and Lou, Zhenkun Z..  (2008)  DBC1 is a negative regulator of SIRT1..  Nature,    (31):   [PMID:18235501]
97. Zhao, Wenhui W and 5 more authors..  (2008)  Negative regulation of the deacetylase SIRT1 by DBC1..  Nature,    (31):   [PMID:18235502]
98. Kwon, Hye-Sook HS and 9 more authors..  (2008)  Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation..  Cell host & microbe,    (13):   [PMID:18329615]
99. Murayama, Akiko A and 13 more authors..  (2008)  Epigenetic control of rDNA loci in response to intracellular energy status..  Cell,    (16):   [PMID:18485871]
100. Asher, Gad G and 8 more authors..  (2008)  SIRT1 regulates circadian clock gene expression through PER2 deacetylation..  Cell,    (25):   [PMID:18662546]
101. Lan, Fan F, Cacicedo, Jose M JM, Ruderman, Neil N and Ido, Yasuo Y..  (2008)  SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation..  The Journal of biological chemistry,    (10):   [PMID:18687677]
102. Ford, Jack J, Ahmed, Shafiq S, Allison, Simon S, Jiang, Ming M and Milner, Jo J..  (2008)  JNK2-dependent regulation of SIRT1 protein stability..  Cell cycle (Georgetown, Tex.),      [PMID:18838864]
103. Sasaki, Tsutomu T and 7 more authors..  (2008)  Phosphorylation regulates SIRT1 function..  PloS one,      [PMID:19107194]
104. Pediconi, Natalia N and 8 more authors..  (2009)  hSirT1-dependent regulation of the PCAF-E2F1-p73 apoptotic pathway in response to DNA damage..  Molecular and cellular biology,      [PMID:19188449]
105. Du, Jintang J, Jiang, Hong H and Lin, Hening H..  (2009)  Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD..  Biochemistry,    (7):   [PMID:19220062]
106. Zschoernig, Barbara B and Mahlknecht, Ulrich U..  (2009)  Carboxy-terminal phosphorylation of SIRT1 by protein kinase CK2..  Biochemical and biophysical research communications,    (10):   [PMID:19236849]
107. Purushotham, Aparna A and 5 more authors..  (2009)  Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation..  Cell metabolism,      [PMID:19356714]
108. Yuan, Jian J, Minter-Dykhouse, Katherine K and Lou, Zhenkun Z..  (2009)  A c-Myc-SIRT1 feedback loop regulates cell growth and transformation..  The Journal of cell biology,    (20):   [PMID:19364925]
109. Xie, Yuan-Bin YB and 8 more authors..  (2009)  Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation..  The Journal of biological chemistry,    (16):   [PMID:19690166]
110. Mayya, Viveka V and 7 more authors..  (2009)  Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions..  Science signaling,    (18):   [PMID:19690332]
111. Yamamori, Tohru T and 8 more authors..  (2010)  SIRT1 deacetylates APE1 and regulates cellular base excision repair..  Nucleic acids research,      [PMID:19934257]
112. Nasrin, Nargis N and 6 more authors..  (2009)  JNK1 phosphorylates SIRT1 and promotes its enzymatic activity..  PloS one,    (22):   [PMID:20027304]
113. Uhl, Miriam M and 5 more authors..  (2010)  Role of SIRT1 in homologous recombination..  DNA repair,    (4):   [PMID:20097625]
114. Wang, Jiadong J and Chen, Junjie J..  (2010)  SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60..  The Journal of biological chemistry,    (9):   [PMID:20100829]
115. Guo, Xiumei X, Williams, Jason G JG, Schug, Thaddeus T TT and Li, Xiaoling X..  (2010)  DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1..  The Journal of biological chemistry,    (23):   [PMID:20167603]
116. Ghosh, Hiyaa Singhee HS, McBurney, Michael M and Robbins, Paul D PD..  (2010)  SIRT1 negatively regulates the mammalian target of rapamycin..  PloS one,    (15):   [PMID:20169165]
117. Zu, Yi Y and 7 more authors..  (2010)  SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells..  Circulation research,    (30):   [PMID:20203304]
118. Chanda, Dipanjan D, Xie, Yuan-Bin YB and Choi, Hueng-Sik HS..  (2010)  Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation..  Nucleic acids research,      [PMID:20375098]
119. Lim, Ji-Hong JH and 5 more authors..  (2010)  Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha..  Molecular cell,    (25):   [PMID:20620956]
120. Fan, Wei W and Luo, Jianyuan J..  (2010)  SIRT1 regulates UV-induced DNA repair through deacetylating XPA..  Molecular cell,    (30):   [PMID:20670893]
121. Ponugoti, Bhaskar B and 9 more authors..  (2010)  SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism..  The Journal of biological chemistry,    (29):   [PMID:20817729]
122. Wang, Feng-Ming FM, Chen, Yi-Jiun YJ and Ouyang, Hong-Jiao HJ..  (2011)  Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation..  The Biochemical journal,    (1):   [PMID:20955178]
123. Lynch, Cian J and 8 more authors..  (2010)  SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53..  PloS one,    (21):   [PMID:20975832]
124. Ming, Mei M and 6 more authors..  (2010)  Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C..  Proceedings of the National Academy of Sciences of the United States of America,    (28):   [PMID:21149730]
125. Yuan, Fang F and 10 more authors..  (2011)  MST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylation..  The Journal of biological chemistry,    (4):   [PMID:21212262]
126. Liu, Xiangyu X and 9 more authors..  (2011)  Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1)..  Proceedings of the National Academy of Sciences of the United States of America,    (1):   [PMID:21245319]
127. Dvir-Ginzberg, Mona M and 5 more authors..  (2011)  Tumor necrosis factor α-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytes..  Arthritis and rheumatism,      [PMID:21305533]
128. Rigbolt, Kristoffer T G KT and 9 more authors..  (2011)  System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation..  Science signaling,    (15):   [PMID:21406692]
129. Back, Jung Ho JH and 6 more authors..  (2011)  Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent Inhibition of sirtuin 1..  The Journal of biological chemistry,    (27):   [PMID:21471201]
130. Bosch-Presegué, Laia L and 7 more authors..  (2011)  Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection..  Molecular cell,    (22):   [PMID:21504832]
131. Pradhan, Anjan Kumar AK, Kuila, Nivedita N, Singh, Sneha S and Chakraborty, Soumen S..  ()  EVI1 up-regulates the stress responsive gene SIRT1 which triggers deacetylation and degradation of EVI1..  Biochimica et biophysica acta,      [PMID:21555002]
132. Marshall, Glenn M GM and 19 more authors..  (2011)  SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability..  PLoS genetics,      [PMID:21698133]
133. Hirschey, Matthew D MD, Shimazu, Tadahiro T, Capra, John A JA, Pollard, Katherine S KS and Verdin, Eric E..  (2011)  SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2..  Aging,      [PMID:21701047]
134. Sundaresan, Nagalingam R NR and 9 more authors..  (2011)  The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy..  Science signaling,    (19):   [PMID:21775285]
135. Mao, Beibei B and 7 more authors..  (2011)  Sirt1 deacetylates c-Myc and promotes c-Myc/Max association..  The international journal of biochemistry & cell biology,      [PMID:21807113]
136. Wang, F F and 5 more authors..  (2012)  Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation..  Oncogene,    (22):   [PMID:21841822]
137. Wu, Xiaoyan X and 17 more authors..  (2011)  SIRT1 links CIITA deacetylation to MHC II activation..  Nucleic acids research,      [PMID:21890893]
138. Rizki, Gizem G and 7 more authors..  (2011)  The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO..  PLoS genetics,      [PMID:21909281]
139. Peng, Lirong L and 9 more authors..  (2011)  SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities..  Molecular and cellular biology,      [PMID:21947282]
140. Oppenheimer, Hanna H and 8 more authors..  (2012)  75-kd sirtuin 1 blocks tumor necrosis factor α-mediated apoptosis in human osteoarthritic chondrocytes..  Arthritis and rheumatism,      [PMID:21987377]
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142. Miki, Takao T and 8 more authors..  (2012)  PML regulates PER2 nuclear localization and circadian function..  The EMBO journal,    (21):   [PMID:22274616]
143. Van Damme, Petra P and 15 more authors..  (2012)  N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB..  Proceedings of the National Academy of Sciences of the United States of America,    (31):   [PMID:22814378]
144. Dominy, John E JE and 15 more authors..  (2012)  The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis..  Molecular cell,    (28):   [PMID:23142079]
145. Kim, Wootae W and Kim, Ja-Eun JE..  (2013)  Deleted in breast cancer 1 (DBC1) deficiency results in apoptosis of breast cancer cells through impaired responses to UV-induced DNA damage..  Cancer letters,    (10):   [PMID:23352644]
146. Hubbard, Basil P and 29 more authors..  (2013)  Evidence for a common mechanism of SIRT1 regulation by allosteric activators..  Science (New York, N.Y.),    (8):   [PMID:23471411]
147. Lakshminarasimhan, Mahadevan; Rauh, David; Schutkowski, Mike and Steegborn, Clemens..  (2013)  Sirt1 activation by resveratrol is substrate sequence-selective..  Aging,      [PMID:23524286]
148. Laurent, Gaëlle G and 10 more authors..  (2013)  SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation..  Molecular and cellular biology,      [PMID:24043310]
149. Hoffmann, Gesine G, Breitenbücher, Frank F, Schuler, Martin M and Ehrenhofer-Murray, Ann E AE..  (2014)  A novel sirtuin 2 (SIRT2) inhibitor with p53-dependent pro-apoptotic activity in non-small cell lung cancer..  The Journal of biological chemistry,    (21):   [PMID:24379401]
150. Nin, Veronica V, Chini, Claudia C S CC, Escande, Carlos C, Capellini, Verena V and Chini, Eduardo N EN..  (2014)  Deleted in breast cancer 1 (DBC1) protein regulates hepatic gluconeogenesis..  The Journal of biological chemistry,    (28):   [PMID:24415752]
151. Pangon, Laurent L and 8 more authors..  (2015)  MCC inhibits beta-catenin transcriptional activity by sequestering DBC1 in the cytoplasm..  International journal of cancer,    (1):   [PMID:24824780]
152. Magni, Martina M and 7 more authors..  (2014)  Chk2 and REGγ-dependent DBC1 regulation in DNA damage induced apoptosis..  Nucleic acids research,    (1):   [PMID:25361978]
153. Park, Jong Ho JH and 9 more authors..  (2014)  Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage..  Nature communications,    (18):   [PMID:25406032]
154. Sakurabashi, Ayako A and 12 more authors..  (2015)  CCAR2 negatively regulates nuclear receptor LXRα by competing with SIRT1 deacetylase..  The Journal of steroid biochemistry and molecular biology,      [PMID:25661920]
155. Olson, Heather E HE and 57 more authors..  (2018)  A Recurrent De Novo PACS2 Heterozygous Missense Variant Causes Neonatal-Onset Developmental Epileptic Encephalopathy, Facial Dysmorphism, and Cerebellar Dysgenesis..  American journal of human genetics,    (3):   [PMID:29656858]
156. Li, Terytty Yang TY and 16 more authors..  (2018)  Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate..  Nature communications,    (15):   [PMID:29765047]
157. Latorre-Muro, Pedro P and 9 more authors..  (2018)  Dynamic Acetylation of Phosphoenolpyruvate Carboxykinase Toggles Enzyme Activity between Gluconeogenic and Anaplerotic Reactions..  Molecular cell,    (6):   [PMID:30193097]
158. Dalal, Sayli; Deshmukh, Prashant; Unni, Sruthi; Padavattan, Sivaraman and Padmanabhan, Balasundaram..  (2019)  Biochemical insight into pseudouridine synthase 7 (PUS7) as a novel interactor of sirtuin, SIRT1..  Biochemical and biophysical research communications,    (20):   [PMID:31451225]
159. Wang, Jiajia and 11 more authors..  (2020)  Acetylation of XPF by TIP60 facilitates XPF-ERCC1 complex assembly and activation..  Nature communications,    (7):   [PMID:32034146]

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