Recombinant SLAMF6 Antibody - Primary antibody, specific to SLAMF6, Rabbit IgG
Synonyms
Activating NK receptor | NK-T-B-antigen | NTB-A | Activating NK receptor antibody | CD352 antibody | KALI antibody | KALIb antibody | LY108 antibody | MGC104953 antibody | Natural killer T and B cell antigen antibody | NK T B antigen antibody | NK-, T-, a
Specifications & Purity
ExactAb™, Validated, Recombinant, 0.5 mg/mL
Host species
Rabbit
Specificity
SLAMF6
Immunogen
Recombinant protein of human SLAMF6 (AA 24-215)
Positive Control
WB: Ramos, Jurkat, MOLT-4 and Raji cell lysates.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Product Description
Rabbit anti Human SLAMF6 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.
Product Properties
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Antigen affinity purified
Form
Liquid
Concentration
0.5 mg/mL
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
Recombinant SLAMF6 Antibody (Ab127767) - Western Blot All lanes: Recombinant SLAMF6 Antibody (Ab127767) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 37 kDa Observed band size: 58 kDa Exposure time: 30.2 s
1.Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C et al.. (2003) The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.. Genome Res, 13 (10):(2265-70). [PMID:12975309]
2.Bottino, C C and 10 more authors.. (2001) NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease.. The Journal of experimental medicine, (6):[PMID:11489943]
3.Zhang, Zemin Z and Henzel, William J WJ.. (2004) Signal peptide prediction based on analysis of experimentally verified cleavage sites.. Protein science : a publication of the Protein Society, [PMID:15340161]
4.Gregory, S G SG and 178 more authors.. (2006) The DNA sequence and biological annotation of human chromosome 1.. Nature, (18):[PMID:16710414]
5.Eissmann, Philipp P and Watzl, Carsten C.. (2006) Molecular analysis of NTB-A signaling: a role for EAT-2 in NTB-A-mediated activation of human NK cells.. Journal of immunology (Baltimore, Md. : 1950), (1):[PMID:16920955]
6.Cao, Erhu E and 8 more authors.. (2006) NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family.. Immunity, [PMID:17045824]
7.Wollscheid, Bernd B and 7 more authors.. (2009) Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.. Nature biotechnology, [PMID:19349973]
8.Mayya, Viveka V and 7 more authors.. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.. Science signaling, (18):[PMID:19690332]
9.Chatterjee, Madhumouli M and 6 more authors.. (2012) Increased expression of SLAM receptors SLAMF3 and SLAMF6 in systemic lupus erythematosus T lymphocytes promotes Th17 differentiation.. Journal of immunology (Baltimore, Md. : 1950), (1):[PMID:22184727]
10.Chatterjee, Madhumouli M and 5 more authors.. (2012) CD3-T cell receptor co-stimulation through SLAMF3 and SLAMF6 receptors enhances RORγt recruitment to the IL17A promoter in human T lymphocytes.. The Journal of biological chemistry, (2):[PMID:22989874]
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.