| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab127927-10μl | 10μl | In stock | $59.90 | |
| Ab127927-50μl | 50μl | In stock | $189.90 | |
| Ab127927-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $279.90 | |
| Ab127927-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,499.90 |
Recombinant; Rabbit anti Human SLC31A1/CTR1 Antibody; WB; Unconjugated
| Product Name | Recombinant SLC31A1/CTR1 Antibody - Primary antibody, specific to SLC31A1/CTR1, Rabbit IgG |
|---|---|
| Synonyms | Copper transport 1 homolog antibody | Copper transporter 1 antibody | COPT1 antibody | COPT1_HUMAN antibody | CTR1 antibody | hCTR1 antibody | High affinity copper uptake protein 1 antibody | SLC31A1 antibody | solute carrier family 31 (copper tansporters |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.2 mg/mL |
| Host species | Rabbit |
| Specificity | SLC31A1/CTR1 |
| Immunogen | A synthetic peptide derived from human SLC31A1/CTR1 (AA 10-23) |
| Positive Control | WB: HeLa, Hep G2, Ramos, HEK293, NIH/3T3 and C6 cell lysates. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description | Rabbit anti Human SLC31A1/CTR1 Antibody, Recombinant, could be used for WB and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Antigen affinity purified |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant SLC31A1/CTR1 Antibody (Ab127927) - Western Blot
All lanes: Recombinant SLC31A1/CTR1 Antibody (Ab127927) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 21 kDa
Observed band size: 27 kDa
Exposure time: 7.7 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000"> 1/500-1/1000 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0303515 | Certificate of Analysis | Mar 22, 2024 | Ab127927 |
| ZJ24F0303514 | Certificate of Analysis | Mar 22, 2024 | Ab127927 |
| 1. Lee J, Peña MM, Nose Y, Thiele DJ. (2002) Biochemical characterization of the human copper transporter Ctr1.. J Biol Chem, 277 (6): (4380-7). [PMID:11734551] [10.1021/op500134e] |
| 2. Zhou, B B and Gitschier, J J.. (1997) hCTR1: a human gene for copper uptake identified by complementation in yeast.. Proceedings of the National Academy of Sciences of the United States of America, (8): [PMID:9207117] |
| 3. Klomp, Adriana E M AE, Tops, Bastiaan B J BB, Van Denberg, Inge E T IE, Berger, Ruud R and Klomp, Leo W J LW.. (2002) Biochemical characterization and subcellular localization of human copper transporter 1 (hCTR1).. The Biochemical journal, (1): [PMID:12023893] |
| 4. Humphray, S J SJ and 147 more authors.. (2004) DNA sequence and analysis of human chromosome 9.. Nature, (27): [PMID:15164053] |
| 5. Guo, Yan Y, Smith, Kathryn K and Petris, Michael J MJ.. (2004) Cisplatin stabilizes a multimeric complex of the human Ctr1 copper transporter: requirement for the extracellular methionine-rich clusters.. The Journal of biological chemistry, (5): [PMID:15326162] |
| 6. Aller, Stephen G SG and Unger, Vinzenz M VM.. (2006) Projection structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture.. Proceedings of the National Academy of Sciences of the United States of America, (7): [PMID:16501047] |
| 7. Molloy, Shannon A SA and Kaplan, Jack H JH.. (2009) Copper-dependent recycling of hCTR1, the human high affinity copper transporter.. The Journal of biological chemistry, (23): [PMID:19740744] |
| 8. Bertinato, Jesse J, Cheung, Lawrence L, Hoque, Rezaul R and Plouffe, Louise J LJ.. (2010) Ctr1 transports silver into mammalian cells.. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), [PMID:20569931] |
| 9. Maryon, Edward B EB, Molloy, Shannon A SA, Ivy, Kristin K, Yu, Huijun H and Kaplan, Jack H JH.. (2013) Rate and regulation of copper transport by human copper transporter 1 (hCTR1).. The Journal of biological chemistry, (21): [PMID:23658018] |
| 10. Öhrvik, Helena H and 6 more authors.. (2013) Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper- and cisplatin-binding ecto-domain.. Proceedings of the National Academy of Sciences of the United States of America, (12): [PMID:24167251] |
| 11. Levy, Ariel R AR, Yarmiayev, Valeria V, Moskovitz, Yoni Y and Ruthstein, Sharon S.. (2014) Probing the structural flexibility of the human copper metallochaperone Atox1 dimer and its interaction with the CTR1 c-terminal domain.. The journal of physical chemistry. B, (5): [PMID:24837030] |
| 12. Tsai, Cheng-Yu CY, Liebig, Janika K JK, Tsigelny, Igor F IF and Howell, Stephen B SB.. (2015) The copper transporter 1 (CTR1) is required to maintain the stability of copper transporter 2 (CTR2).. Metallomics : integrated biometal science, [PMID:26205368] |
| 13. Kahra, Dana D, Kovermann, Michael M and Wittung-Stafshede, Pernilla P.. (2016) The C-Terminus of Human Copper Importer Ctr1 Acts as a Binding Site and Transfers Copper to Atox1.. Biophysical journal, (5): [PMID:26745413] |
| 14. Clifford, Rebecca J RJ, Maryon, Edward B EB and Kaplan, Jack H JH.. (2016) Dynamic internalization and recycling of a metal ion transporter: Cu homeostasis and CTR1, the human Cu⁺ uptake system.. Journal of cell science, (15): [PMID:26945057] |
