| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab130520-10μl | 10μl | In stock | $79.90 | |
| Ab130520-50μl | 50μl | In stock | $239.90 | |
| Ab130520-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $319.90 | |
| Ab130520-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,999.90 |
Recombinant; Rabbit anti Human Tcl1 Antibody; WB; Unconjugated
| Product Name | Recombinant Tcl1 Antibody - Primary antibody, specific to Tcl1, Rabbit IgG |
|---|---|
| Synonyms | TCL1 | Oncogene TCL1 | Oncogene TCL-1 | Protein p14 TCL1 | T-cell leukemia/lymphoma 1A | T-cell lymphoma-1 | T-cell lymphoma-1A | TCL1A | TCL1-PEN | TCL1T-cell leukemia/lymphoma protein 1A | Anti TCL1A antibody | Lymphoma/leukemia, T-cell antibody | Oncog |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.55 mg/mL |
| Host species | Rabbit |
| Specificity | Tcl1 |
| Immunogen | A synthetic peptide derived from human TCL1 (AA 1-45). |
| Positive Control | WB: Ramos lysates. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description | Rabbit anti Human Tcl1 Antibody, Recombinant, could be used for WB and so on. |
| Isotype | Rabbit IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | 0.55 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant Tcl1 Antibody (Ab130520) - Western Blot
All lanes: Recombinant Tcl1 Antibody (Ab130520) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/40000 dilution
Predicted band size: 13 kDa
Observed band size: 15 kDa
Exposure time: 1.0 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000"> 1/500-1/1000 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0303527 | Certificate of Analysis | Mar 22, 2024 | Ab130520 |
| ZJ24F0303526 | Certificate of Analysis | Mar 22, 2024 | Ab130520 |
| 1. Virgilio, L L and 6 more authors.. (1994) Identification of the TCL1 gene involved in T-cell malignancies.. Proceedings of the National Academy of Sciences of the United States of America, (20): [PMID:7809072] |
| 2. Fu, T B TB and 5 more authors.. (1994) Characterization and localization of the TCL-1 oncogene product.. Cancer research, (15): [PMID:7987816] |
| 3. Hoh, F F and 6 more authors.. (1998) Crystal structure of p14TCL1, an oncogene product involved in T-cell prolymphocytic leukemia, reveals a novel beta-barrel topology.. Structure (London, England : 1993), (15): [PMID:9519406] |
| 4. Pekarsky, Y Y and 8 more authors.. (2000) Tcl1 enhances Akt kinase activity and mediates its nuclear translocation.. Proceedings of the National Academy of Sciences of the United States of America, (28): [PMID:10716693] |
| 5. Laine, J J, Künstle, G G, Obata, T T, Sha, M M and Noguchi, M M.. (2000) The protooncogene TCL1 is an Akt kinase coactivator.. Molecular cell, [PMID:10983986] |
| 6. Laine, Jarmo J, Künstle, Gerald G, Obata, Toshiyuki T and Noguchi, Masayuki M.. (2002) Differential regulation of Akt kinase isoforms by the members of the TCL1 oncogene family.. The Journal of biological chemistry, (1): [PMID:11707444] |
| 7. Künstle, Gerald G and 8 more authors.. (2002) Identification of Akt association and oligomerization domains of the Akt kinase coactivator TCL1.. Molecular and cellular biology, [PMID:11839817] |
| 8. French, Samuel W SW and 10 more authors.. (2007) The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity.. Cancer letters, (18): [PMID:16934922] |
