Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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R335710-5mg | 5mg | In stock | $73.90 | |
R335710-25mg | 25mg | In stock | $221.90 | |
R335710-50mg | 50mg | In stock | $343.90 | |
R335710-100mg | 100mg | In stock | $523.90 |
a selective A2A adenosine receptor agonist in myocardial imaging
Synonyms | (1-{9-[(4s,2r,3r,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-n-methylcarboxamide | J-511375 | Tox21_303374 | 2-[4-[(Methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine | AS-56292 | J-018384 | Adenosine, 2-[4-[(methylamino)c |
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Specifications & Purity | Moligand™, ≥98% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of A 1 receptor;Agonist of A 2A receptor;Agonist of A 2B receptor;Agonist of A 3 receptor |
Product Description | Regadenoson is a selective Adenosine A2A-R (A2A adenosine receptor) agonist in myocardial imaging. |
pKa | pKₐ: 13.07, pKₐ: 1.32 |
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Ki Data | Adenosine A2A-R: Ki= 290 nM (human); Adenosine A2A-R: Ki= 290 nM (rat); Adenosine A1-R: Ki>16.46 mM (human) |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 1-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-N-methylpyrazole-4-carboxamide |
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INCHI | InChI=1S/C15H18N8O5/c1-17-13(27)6-2-19-23(3-6)15-20-11(16)8-12(21-15)22(5-18-8)14-10(26)9(25)7(4-24)28-14/h2-3,5,7,9-10,14,24-26H,4H2,1H3,(H,17,27)(H2,16,20,21)/t7-,9-,10-,14-/m1/s1 |
InChi Key | LZPZPHGJDAGEJZ-AKAIJSEGSA-N |
Canonical SMILES | CNC(=O)C1=CN(N=C1)C2=NC(=C3C(=N2)N(C=N3)C4C(C(C(O4)CO)O)O)N |
Isomeric SMILES | CNC(=O)C1=CN(N=C1)C2=NC(=C3C(=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)N |
PubChem CID | 219024 |
Molecular Weight | 390.35 |
CAS Registry No. | 313348-27-5 |
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ChEMBL Ligand | CHEMBL317052 |
Wikipedia | Regadenoson |
DrugBank Ligand | DB06213 |
PubChem CID | 219024 |
DrugCentral Ligand | 2362 |
GPCRdb Ligand | regadenoson |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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G2213167 | Certificate of Analysis | Jun 02, 2022 | R335710 |
G2213169 | Certificate of Analysis | Jun 02, 2022 | R335710 |
G2213170 | Certificate of Analysis | Jun 02, 2022 | R335710 |
G2213172 | Certificate of Analysis | Jun 02, 2022 | R335710 |
Solubility | Soluble in DMSO, and methanol. |
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Refractive Index | n20D1.90 (Predicted) |
Boil Point(°C) | 744.10° C (Predicted) |
Melt Point(°C) | 194-196° C |
Pictogram(s) | GHS06, GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled H300:Fatal if swallowed H310:Fatal in contact with skin H330:Fatal if inhaled H370:Causes damage to organs |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P262:Do not get in eyes, on skin, or on clothing. P320:Specific treatment is urgent (see ... on this label). P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P308+P316:IF exposed or concerned: Get emergency medical help immediately. P332+P317:If skin irritation occurs: Get medical help. P316:Get emergency medical help immediately. |