Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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R107314-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $90.90 |
Antioxidant polyphenol with a multitude of biological activities
Synonyms | resveratrol | 501-36-0 | trans-resveratrol | 3,4',5-Trihydroxystilbene | (E)-5-(4-Hydroxystyryl)benzene-1,3-diol | 3,5,4'-Trihydroxystilbene | (E)-resveratrol | Resvida | 3,4',5-Stilbenetriol | 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol | 3,4',5-Trihydroxy-trans-stil |
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Specifications & Purity | Moligand™, analytical standard |
Biochemical and Physiological Mechanisms | Resveratrol is a phenolic phytoalexin found in grape skin and other plants. Resveratrol produced neurotrophic effects on cultured DA neurons. Resveratrol could attenuate oxidant-induced mitochondrial damage in embryonic rat cardiomyocytes by inactivating |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | analytical standard, Moligand™ |
Action Type | AGONIST, ANTAGONIST, INHIBITOR |
Mechanism of action | Inhibitor of COX-2;Agonist of TAS2R14;Antagonist of Peroxisome proliferator-activated receptor-γ |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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IUPAC Name | 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol |
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INCHI | InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ |
InChi Key | LUKBXSAWLPMMSZ-OWOJBTEDSA-N |
Canonical SMILES | C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O |
Isomeric SMILES | C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O |
WGK Germany | 3 |
RTECS | CZ8987000 |
Alternate CAS | 501-36-0 |
PubChem CID | 445154 |
NSC Number | 327430 |
MeSH Entry Terms | 3,4',5-stilbenetriol;3,4',5-Trihydroxystilbene;3,5,4'-trihydroxystilbene;cis Resveratrol;cis-resveratrol;resveratrol;Resveratrol 3 sulfate;Resveratrol, (Z)-;resveratrol-3-sulfate;SRT 501;SRT-501;SRT501;trans Resveratrol;trans Resveratrol 3 O sulfate;trans |
Molecular Weight | 228.24 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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H1617086 | Certificate of Analysis | Dec 20, 2023 | R107314 |
Melt Point(°C) | 267 °C |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H319:Causes serious eye irritation |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. |
WGK Germany | 3 |
RTECS | CZ8987000 |
Merck Index | 8158 |
1. Song Yu, Lianpeng Zou, Jiawei Zhao, Yiping Zhu. (2023) Resveratrol alleviates fumonisin-induced intestinal cytotoxicity by modulating apoptosis, tight junction, and inflammation in IPEC-J2 porcine intestinal epithelial cells. ENVIRONMENTAL TOXICOLOGY, (15): [PMID:37955343] |
2. Yifan Ma, Yi Qian, Yuteng Chen, Xiaoxu Ruan, Xiaoya Peng, Yi Sun, Jue Zhang, Jingjing Luo, Songlin Zhou, Chao Deng. (2023) Resveratrol modulates the inflammatory response in hPDLSCs via the NRF2/HO-1 and NF-κB pathways and promotes osteogenic differentiation. JOURNAL OF PERIODONTAL RESEARCH, [PMID:37905727] |
3. Dong Wu, Huihui Ming, Wei Wu, Wenjie Yu, Gaowei Zhang, Jinzhu Gu, Meng Cui, Xueyong Huang, Fangjian Ning, Liping Luo. (2024) In situ neutral desorption-extractive electrospray ionization mass spectrometry reveals red-blue light promoted the accumulation of amino acids and polyphenols in Anoectochilus roxburghii. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 125 (105761). [PMID:18810425] |
4. Nayun Kim, Junhye Kwon, Ui Sup Shin, Joohee Jung. (2023) Stimulatory Anticancer Effect of Resveratrol Mediated by G Protein-Coupled Estrogen Receptor in Colorectal Cancer. Biomolecules & Therapeutics, 31 (6): ( 655–660). [PMID:37817377] |
5. Yuan Gu, Yanjun Cai, Yige Kou, Erzhuo Cheng, Hanjie Bi, Min Hu, Songyao Wu, Yong Jiang, Jingxi Zhang, Qingting Wu, Yunyi Li, Bin Yang. (2023) Construction of multifunctional targeted nano-prodrugs based on PAMAM dendrimers for tumor therapy. EUROPEAN POLYMER JOURNAL, 200 (12): (112486). [PMID:21709241] |
6. Liu Xinru, Ma Qianwei, Sun Yongjun, Ju Wenming, Kumrungsee Thanutchaporn, Zhou Zhongkai, Wang Lijuan, Cao Ruge. (2023) Effects of Processings and Complexation on Solubility, Antioxidant and Antibacterial Properties of Buckwheat Polyphenols. Food and Bioprocess Technology, (8): (1-13). [PMID:18063578] |
7. Chen Wang, Ding Tang, Wei Xu, Yan Liu, Zhao-He Huang, Pang-Chui Shaw, Ren-Wang Jiang. (2023) Glycosylation of the polyphenols from Resina draconis by glycosyltransferase YjiC1. NATURAL PRODUCT RESEARCH, [PMID:35437081] |
8. Zhiyu Sun, Yongbin Zhou, Wenxu Zhu, You Yin. (2023) Assessment of the Fruit Chemical Characteristics and Antioxidant Activity of Different Mulberry Cultivars (Morus spp.) in Semi-Arid, Sandy Regions of China. Foods, 12 (18): (3495). [PMID:37761204] |
9. Li Yanyan, Wang Hongling, Shi Haiming, Guo Qin, Zhang Yuquan, Shi Aimin, Jiang Yuanrong, Wang Qiang. (2023) Quantification of Resveratrol in Peanut Oils Using Stable Isotope Dilution Ultra-high Performance Liquid Chromatography-Mass Spectrometry. Food Analytical Methods, 16 (11): (1673-1679). [PMID:17160893] |
10. Yao Ke, Mou Qianxue, Lou Xiaotong, Ye Meng, Zhao Bowen, Hu Yuanyuan, Luo Jing, Zhang Hong, Li Xing, Zhao Yin. (2023) Microglial SIRT1 activation attenuates synapse loss in retinal inner plexiform layer via mTORC1 inhibition. Journal of Neuroinflammation, 20 (1): (1-18). [PMID:37670386] |
11. Yajie Zhang, Changjiao Shang, Chaofan Sun, Lingling Wang. (2024) Simultaneously regulating absorption capacities and antioxidant activities of four stilbene derivatives utilizing substitution effect: A theoretical and experimental study against UVB radiation. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 304 (123325). [PMID:37678043] |
12. Chen-Xi Bi, Kai-Qi Jin, Jing Yan, Yu Qin, Feng Hong, Wei-Hua Huang, Yan-Ling Liu. (2023) Nanofiber-based Stretchable Electrodes for Oriented Culture and Mechanotransduction Monitoring of Smooth Muscle Cells. ACS Sensors, 8 (8): (3248–3256). [PMID:37581426] |
13. Lu Tan, Menghuan Li, Hang Chen, Yuchen Zhang, Yuan Liu, Maohua Chen, Zhong Luo, Kaiyong Cai, Yan Hu. (2023) Dynamic hydrogel with environment-adaptive autonomous wound-compressing ability enables rapid hemostasis and inflammation amelioration for hemorrhagic wound healing. Nano Today, 52 (101962). [PMID:] |
14. Hao Guan, Zhiyong Li, Qinlong Xu, Jingjing Meng, Kai Guo. (2023) Dual bio-based epoxy resin as green substitute for DGEBA analogue with high performances. REACTIVE & FUNCTIONAL POLYMERS, 191 (105687). [PMID:] |
15. Minghui Cai, Haijuan Sun, Yujia Huang, Haixu Yao, Chen Zhao, Jiao Wang, Hui Zhu. (2023) Resveratrol Protects Rat Ovarian Luteinized Granulosa Cells from H2O2-Induced Dysfunction by Activating Autophagy. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (13): (10914). [PMID:37446088] |
16. Maolin Li, Xin Zhang, Dandan Han, Songgu Wu, Junbo Gong. (2023) Systematic study on lysozyme-hyaluronan complexes: Multi-spectroscopic characterization and molecular dynamics simulation. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 246 (125642). [PMID:37394210] |
17. Song Yu, Lianpeng Zou, Jiawei Zhao, Yiping Zhu. (2023) Individual and Combined Cytotoxic Effects of Co-Occurring Fumonisin Family Mycotoxins on Porcine Intestinal Epithelial Cell. Foods, 12 (13): (2555). [PMID:37444293] |
18. Duoduo Li, Zihao Wei, Xiaolong Li. (2023) Development, Characterization and Resveratrol Delivery of Hollow Gliadin Nanoparticles: Advantages over Solid Gliadin Nanoparticles. Foods, 12 (13): (2436). [PMID:37444174] |
19. Feifei Liu, Ying Chen, Jianle Chen, Enbo Xu, Haibo Pan, Shiguo Chen, Xingqian Ye, Huan Cheng. (2023) Characteristic aroma improvement mechanisms of heat-sterilized bayberry juice regulated by exogenous polyphenols. FOOD CHEMISTRY, 427 (136644). [PMID:37390737] |
20. Chen Shengnan, Li Bo, Chen Lei, Jiang Hongli. (2023) Uncovering the mechanism of resveratrol in the treatment of diabetic kidney disease based on network pharmacology, molecular docking, and experimental validation. Journal of Translational Medicine, 21 (1): (1-14). [PMID:37308949] |
21. Weiwei Wang, Xin Li, Qiuhui Qian, Jin Yan, Haishan Huang, Xuedong Wang, Huili Wang. (2023) Mechanistic exploration on neurodevelopmental toxicity induced by upregulation of alkbh5 targeted by triclosan exposure to larval zebrafish. JOURNAL OF HAZARDOUS MATERIALS, 457 (131831). [PMID:37320907] |
22. Ye Shu, Tong Chen, Tao Liu, Hechen Xu, Jinjin He, Zhihui Cai, Wanning Zhu, Zihan Zhao, Jun Jiang. (2023) Preparation and characterization of mixed-mode hydrophilic stationary phase based on triple hydrophilic functionalized moieties and its application to traditional Chinese herbal compound. MICROCHEMICAL JOURNAL, 191 (108863). [PMID:] |
23. Yanwei Li, Susu Wang, Yurong Li, Guozheng Zhang, Tangfeng Wu, Yongkang Wei, Xinyu Cao, Hui Yan, Peisheng Liang, Zihan Yan, Yanan Guo, Yeshun Zhang. (2023) Resveratrol loaded native silk fiber-sericin hydrogel double interpenetrating bioactive wound dressing facilitates full-thickness skin wound healing. Biomedical Materials, 18 (4): (45007). [PMID:37146618] |
24. Cai Weiye, Sun Bin, Song Chao, Liu Fei, Wu Zhengliang, Liu Zongchao. (2023) Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy. BMC Complementary Medicine and Therapies, 23 (1): (1-11). [PMID:37060066] |
25. Yi Ou, Zonglin You, Min Yao, Yingfan Cao, Xiu Xue, Min Chen, Rihui Wu, Lishe Gan, Dongli Li, Panpan Wu, Xuetao Xu, Wingleung Wong, Vincent Kam Wai Wong, Wenfeng Liu, Jiming Ye, Jingwei Jin. (2023) Naproxen-Derived New Compound Inhibits the NF-κB, MAPK and PI3K/Akt Signaling Pathways Synergistically with Resveratrol in RAW264.7 Cells. MOLECULES, 28 (8): (3395). [PMID:37110629] |
26. Ting Qin, Kai Chen, Bingwen Xi, Liangkun Pan, Jun Xie, Liushen Lu, Kai Liu. (2023) In Vitro Antibiofilm Activity of Resveratrol against Aeromonas hydrophila. Antibiotics-Basel, 12 (4): (686). [PMID:37107048] |
27. Fangyuan Jing, Yuda Zhu, Fan Li, Yilan Wang, Xiuxian Yu, Kun Zhang, Guang Xin, Wen Huang. (2023) Bimetallic ions-doped carbon dots nanotheranostics for imaging-guided macrophage polarization/ROS scavenging in acute pancreatitis. CHEMICAL ENGINEERING JOURNAL, 465 (142675). [PMID:] |
28. Zhaolun Li, Hongyan Wu, Jianan Liu, Hongshun Hao, Jingran Bi, Hongman Hou, Gongliang Zhang. (2023) Synergistic effects of benzyl isothiocyanate and resveratrol against Listeria monocytogenes and their application in chicken meat preservation. FOOD CHEMISTRY, 419 (135984). [PMID:37044056] |
29. Jiaming Liu, Xiaohong Liu, Xiaohua Cui, Jingjing Qin, Mengqin Wu, Lifu Fu, Min Shi, Dingsong Wang, Liyan Liang. (2023) Investigation on the properties and structures of resveratrol-derived epoxy thermosets cured with an active ester. Polymer Chemistry, 14 (14): (1665-1679). [PMID:] |
30. Simin Deng, Yuan Xu, Binbin Gao, Tingting Yu, Lun Kuang, Bo’ang Han, Shaolun Feng, Haodong Chi, Qing Cao, Shen Yue, Chen Liu. (2023) Anemarrhenasaponin I suppresses ovarian cancer progression via inhibition of SHH signaling pathway. Oncologie, 25 (3): (233-243). [PMID:] |
31. Lili Cao, Pengpeng Jia, Haotian Liu, Shengmei Kang, Shaotong Jiang, Min Pang. (2023) Effects of High-Canolol Phenolic Extracts on Fragrant Rapeseed Oil Quality and Flavor Compounds during Frying. Foods, 12 (4): (827). [PMID:36832902] |
32. Zhang Qian, Chuwei Li, Wei Zhao, Zhaowanyue He, Mengqi Xue, Shuxian Wang, Xi Cheng, Rujun Ma, Xie Ge. (2023) Chronic oral exposure to short chain chlorinated paraffins induced testicular toxicity by promoting NRF2-mediated oxidative stress. TOXICOLOGY LETTERS, 376 (1). [PMID:36642205] |
33. Xiaoxiang Gao, Chenbo Yue, Ruocen Tian, Leilei Yu, Fengwei Tian, Jianxin Zhao, Wei Chen, Qixiao Zhai. (2023) The regulatory effects of specific polyphenols on Akkermansia are dependent on uridine. FOOD CHEMISTRY, 410 (135367). [PMID:36610089] |
34. Xing Yunliang, Zhang Yuan, He Xianru. (2023) Design of acetylene-modified bio-based tri-functional benzoxazine and its copolymerization with bismaleimide for performance enhancement. POLYMER BULLETIN, 80 (11): (12065-12077). [PMID:] |
35. Lanxin Bao, Jing Ye, Nannan Liu, Yubao Shao, Wenhao Li, Xuefei Fan, Dahai Zhao, Hongzhi Wang, Xiaoyu Chen. (2022) Resveratrol Ameliorates Fibrosis in Rheumatoid Arthritis-Associated Interstitial Lung Disease via the Autophagy–Lysosome Pathway. MOLECULES, 27 (23): (8475). [PMID:36500562] |
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52. Zhaolun Li, Hongyan Wu, Jianan Liu, Hongshun Hao, Jingran Bi, Hongman Hou, Gongliang Zhang. (2023) Synergistic effects of benzyl isothiocyanate and resveratrol against Listeria monocytogenes and their application in chicken meat preservation. FOOD CHEMISTRY, 419 (135984). [PMID:37044056] |
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54. Simin Deng, Yuan Xu, Binbin Gao, Tingting Yu, Lun Kuang, Bo’ang Han, Shaolun Feng, Haodong Chi, Qing Cao, Shen Yue, Chen Liu. (2023) Anemarrhenasaponin I suppresses ovarian cancer progression via inhibition of SHH signaling pathway. Oncologie, 25 (3): (233-243). [PMID:] |
55. Lili Cao, Pengpeng Jia, Haotian Liu, Shengmei Kang, Shaotong Jiang, Min Pang. (2023) Effects of High-Canolol Phenolic Extracts on Fragrant Rapeseed Oil Quality and Flavor Compounds during Frying. Foods, 12 (4): (827). [PMID:36832902] |
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59. Lanxin Bao, Jing Ye, Nannan Liu, Yubao Shao, Wenhao Li, Xuefei Fan, Dahai Zhao, Hongzhi Wang, Xiaoyu Chen. (2022) Resveratrol Ameliorates Fibrosis in Rheumatoid Arthritis-Associated Interstitial Lung Disease via the Autophagy–Lysosome Pathway. MOLECULES, 27 (23): (8475). [PMID:36500562] |
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72. Ziting Zhang, You Ji, Nan Hu, Qinqi Yu, Xinrui Zhang, Jie Li, Fenglei Wu, Huae Xu, Qiyun Tang, Xiaolin Li. (2022) Ferroptosis-induced anticancer effect of resveratrol with a biomimetic nano-delivery system in colorectal cancer treatment. Asian Journal of Pharmaceutical Sciences, 17 (751). [PMID:36382309] |
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82. Mehmood Sahid, Uddin Md Alim, Yu Haojie, Wang Li, Amin Bilal Ul, Haq Fazal, Fahad Shah, Haroon Muhammad. (2022) Preparation of size-controlled poly(cyclotriphosphazene-co-resveratrol) microspheres and their properties as drug delivery carriers. IRANIAN POLYMER JOURNAL, 31 (10): (1225-1235). [PMID:] |
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