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Retinoic acid - 98%, high purity , CAS No.302-79-4

  • Moligand™
  • ≥98%
Item Number
R106320
Grouped product items
SKUSizeAvailabilityPrice Qty
R106320-500mg
500mg
In stock
$76.90
R106320-1g
1g
In stock
$94.90
R106320-5g
5g
In stock
$427.90
R106320-10g
10g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$769.90
R106320-25g
25g
In stock
$1,731.90
R106320-100g
100g
In stock
$6,232.90

Vitamin A metabolite. Stem cell differentiator.

Basic Description

SynonymsRetinoic acid|tretinoin|302-79-4|all-trans-Retinoic acid|Vitamin A acid|trans-Retinoic acid|ATRA|Renova|Retin-A|Vesanoid|Aberel|Eudyna|Airol|All-trans Retinoic Acid|all-trans-Vitamin A acid|Dermairol|Aknefug|Aknoten|Atralin|Cordes vas|Epi-aberel|TRETINON|
Specifications & Purity98%
Storage TempStore at -20°C,Argon charged
Shipped InDry ice
GradeMoligand™
Product Description

all?trans?Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons.

Product Properties

ALogP6.3

Associated Targets

RARG Tclin Retinoic acid receptor gamma 44 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RXRG Tclin Retinoic acid receptor RXR-gamma 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RXRB Tclin Retinoic acid receptor RXR-beta 3 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RORB Tchem Nuclear receptor ROR-beta 3 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RXRA Tclin Retinoic acid receptor RXR-alpha 4 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 3 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RARB Tclin Retinoic acid receptor beta 44 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RARA Tclin Retinoic acid receptor alpha 31 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR2C2 Tchem Nuclear receptor subfamily 2 group C member 2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

APP Tclin Amyloid-beta A4 protein 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARD Tchem Peroxisome proliferator-activated receptor delta 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
INCHI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
InChi Key SHGAZHPCJJPHSC-YCNIQYBTSA-N
Canonical SMILES CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
Isomeric SMILES CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C
WGK Germany 2
RTECS VH6475000
PubChem CID 444795
Molecular Weight 300.44
Beilstein 2057223
Reaxy-Rn 2057223

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

10 results found

Lot NumberCertificate TypeDateItem
C2429737Certificate of AnalysisMar 08, 2024 R106320
D2418103Certificate of AnalysisJul 28, 2022 R106320
K2215765Certificate of AnalysisJul 28, 2022 R106320
K2215886Certificate of AnalysisJul 28, 2022 R106320
K2215888Certificate of AnalysisJul 28, 2022 R106320
K2215889Certificate of AnalysisJul 28, 2022 R106320
K2215890Certificate of AnalysisJul 28, 2022 R106320
F2406031Certificate of AnalysisDec 09, 2021 R106320
G2315039Certificate of AnalysisDec 09, 2021 R106320
L2103038Certificate of AnalysisDec 09, 2021 R106320

Chemical and Physical Properties

SolubilitySoluble in ethanol, acetate, dimethyl formamide, dimethyl sulfoxide, chloroform, methanol, acetone and dichloromethane. Insoluble in water and ether.
Sensitivityair & light sensitive;
Melt Point(°C)180-181°C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H360:May damage fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 2
RTECS VH6475000
Reaxy-Rn 2057223
Merck Index 8165

Related Documents

FAQs and Articles

References

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