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Retinoic acid - analytical standard, high purity , Retinoic acid receptor agonist, CAS No.302-79-4, Retinoic acid receptor agonist

  • analytical standard
  • Moligand™
Item Number
R106321
Grouped product items
SKUSizeAvailabilityPrice Qty
R106321-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$206.90

Basic Description

SynonymsRetinoic acid|tretinoin|302-79-4|all-trans-Retinoic acid|Vitamin A acid|trans-Retinoic acid|ATRA|Renova|Retin-A|Vesanoid|Aberel|Eudyna|Airol|All-trans Retinoic Acid|all-trans-Vitamin A acid|Dermairol|Aknefug|Aknoten|Atralin|Cordes vas|Epi-aberel|TRETINON|
Specifications & PurityMoligand™, analytical standard
Biochemical and Physiological Mechanisms

Description: IC50 Value: N/A All-trans retinoic acid (ATRA) has been widely investigated for treatments of many cancers including prostate cancer. in vitro: ATRA was able to induce the growth arrest and to increase HOXB13 expression in AR

Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Gradeanalytical standard, Moligand™
Action TypeAGONIST, ANTAGONIST
Mechanism of actionRetinoic acid receptor agonist

Product Properties

ALogP6.3

Names and Identifiers

IUPAC Name (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
INCHI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
InChi Key SHGAZHPCJJPHSC-YCNIQYBTSA-N
Canonical SMILES CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
Isomeric SMILES CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C
WGK Germany 2
RTECS VH6475000
PubChem CID 444795
Molecular Weight 300.44
Beilstein 2057223
Reaxy-Rn 2057223

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

3 results found

Lot NumberCertificate TypeDateItem
F1828090Certificate of AnalysisNov 07, 2023 R106321
L2103040Certificate of AnalysisSep 18, 2023 R106321
F1821031Certificate of AnalysisFeb 22, 2022 R106321

Chemical and Physical Properties

Melt Point(°C)180-181°C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H360:May damage fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 2
RTECS VH6475000
Reaxy-Rn 2057223
Merck Index 8165

Related Documents

References

1. Charton J, Deprez-Poulain R, Hennuyer N, Tailleux A, Staels B, Deprez B.  (2009)  Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives..  Bioorg Med Chem Lett,  19  (2): (489-92).  [PMID:19058965]

Solution Calculators