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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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R648860-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $60.90 | |
R648860-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $90.90 | |
R648860-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $290.90 | |
R648860-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $520.90 |
Specifications & Purity | ≥99% |
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Biochemical and Physiological Mechanisms | Retro-2 cycl (RN 1-001) is a dihydroquinazolinone (DHQZ) inhibitor of retrograde trafficking. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus with IC 50 s of 54 μM and 160 μM, respectively. Antiviral agent. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | Retro-2 cycl (RN 1-001) is a dihydroquinazolinone (DHQZ) inhibitor of retrograde trafficking. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus with IC 50 s of 54 μM and 160 μM, respectively. Antiviral agent. Form:Solid |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2-(5-methylthiophen-2-yl)-3-phenyl-1,2-dihydroquinazolin-4-one |
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INCHI | InChI=1S/C19H16N2OS/c1-13-11-12-17(23-13)18-20-16-10-6-5-9-15(16)19(22)21(18)14-7-3-2-4-8-14/h2-12,18,20H,1H3 |
InChi Key | BOAPXDSRULBILC-UHFFFAOYSA-N |
Canonical SMILES | CC1=CC=C(S1)C2NC3=CC=CC=C3C(=O)N2C4=CC=CC=C4 |
Isomeric SMILES | CC1=CC=C(S1)C2NC3=CC=CC=C3C(=O)N2C4=CC=CC=C4 |
WGK Germany | 3 |
PubChem CID | 71716811 |
Molecular Weight | 320.41 |
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Solubility | DMSO : ≥ 125 mg/mL (390.13 mM) |
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WGK Germany | 3 |
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RIDADR | NONHforallmodesoftransport |