JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

Home
Chemistry & Biochemicals
Biochemicals
Antibiotics
Reveromycin B - >90%, high purity , CAS No.144860-68-4

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Reveromycin B - >90%, high purity , CAS No.144860-68-4

≥90%

CAS#: 144860-68-4
Formula: C₃₆H₅₂O₁₁
Molecular Weight: 660.8
PubChem CID: 10865248

Item Number

R329692

Grouped product items
SKU	Size	Availability	Price	Qty
R329692-250μg	250μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$370.90

a novel polyketide type antibiotic shown inhibit mitogenic activity

Basic Description

Specifications & Purity	≥90%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Reveromycin B is a novel polyketide type antibiotic reveromycin B is a much less active analogue of reveromycin A formed by rearrangement of the 6:6 spiroketal to a 5:6 spiroketal. Lacking much of the biological activity of reveromycin A, reveromycin B is a useful negative control in resolving the mode of action of this class. It has shown to be an inhibitor of the mitogenic activity of epidermal growth factor.

Product Properties

pKa	pKₐ: 4.31 (Predicted)

Associated Targets(non-human)

ileS Isoleucyl-tRNA synthetase (49 Activities)

Discover Target: ileS

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NRK (373 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2E,4S,5S,6E,8E)-10-[(2R,5S,8S,9R)-2-butyl-2-[(1S,2E,4E)-5-carboxy-1-(3-carboxypropanoyloxy)-4-methylpenta-2,4-dienyl]-8-methyl-1,10-dioxaspiro[4.5]decan-9-yl]-5-hydroxy-4,8-dimethyldeca-2,6,8-trienoic acid
INCHI	InChI=1S/C36H52O11/c1-6-7-19-35(30(14-10-25(3)23-33(42)43)45-34(44)17-16-32(40)41)21-22-36(47-35)20-18-27(5)29(46-36)13-9-24(2)8-12-28(37)26(4)11-15-31(38)39/h8-12,14-15,23,26-30,37H,6-7,13,16-22H2,1-5H3,(H,38,39)(H,40,41)(H,42,43)/b12-8+,14-10+,15-11+,24-9+,25-23+/t26-,27-,28-,29+,30-,35+,36-/m0/s1
InChi Key	XVFQIVPMOPJEIO-OXVOKJAASA-N
Canonical SMILES	CCCCC1(CCC2(O1)CCC(C(O2)CC=C(C)C=CC(C(C)C=CC(=O)O)O)C)C(C=CC(=CC(=O)O)C)OC(=O)CCC(=O)O
Isomeric SMILES	CCCC[C@@]1(CC[C@@]2(O1)CC[C@@H]([C@H](O2)C/C=C(\C)/C=C/[C@@H]([C@@H](C)/C=C/C(=O)O)O)C)[C@H](/C=C/C(=C/C(=O)O)/C)OC(=O)CCC(=O)O
PubChem CID	10865248
Molecular Weight	660.8

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Solubility	Soluble in ethyl acetate, ethanol, methanol, DMF, and DMSO.
Refractive Index	n20D1.56 (Predicted)
Boil Point(°C)	848.97° C at 760 mmHg (Predicted)

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.