Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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R127721-5mg | 5mg | In stock | $58.90 | |
R127721-10mg | 10mg | In stock | $105.90 | |
R127721-25mg | 25mg | In stock | $127.90 | |
R127721-50mg | 50mg | In stock | $147.90 | |
R127721-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $246.90 | |
R127721-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $555.90 |
Synonyms | RG2833|1215493-56-3|RG-2833|N-(6-((2-Aminophenyl)amino)-6-oxohexyl)-4-methylbenzamide|RGFP 109|RGFP-109|RGFP109|RG2833 (RGFP109)|N-(6-(2-Aminophenylamino)-6-oxohexyl)-4-methylbenzamide|17V14R89EU|N-[6-(2-aminoanilino)-6-oxohexyl]-4-methylbenzamide|N-[6-(2 |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Description: IC50 Value: N/A RGFP 109 is a histone deacetylase inhibitor which can attenuate L-DOPA-induced dyskinesia in the MPTP-lesioned marmoset. in vitro: N/A in vivo: RGFP109 had no acute effects on dyskinesia after single or 6 days once-daily trea |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of histone deacetylase 1;Inhibitor of histone deacetylase 3 |
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IUPAC Name | N-[6-(2-aminoanilino)-6-oxohexyl]-4-methylbenzamide |
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INCHI | InChI=1S/C20H25N3O2/c1-15-10-12-16(13-11-15)20(25)22-14-6-2-3-9-19(24)23-18-8-5-4-7-17(18)21/h4-5,7-8,10-13H,2-3,6,9,14,21H2,1H3,(H,22,25)(H,23,24) |
InChi Key | VOPDXHFYDJAYNS-UHFFFAOYSA-N |
Canonical SMILES | CC1=CC=C(C=C1)C(=O)NCCCCCC(=O)NC2=CC=CC=C2N |
Isomeric SMILES | CC1=CC=C(C=C1)C(=O)NCCCCCC(=O)NC2=CC=CC=C2N |
PubChem CID | 56654642 |
Molecular Weight | 339.43 |
PubChem CID | 56654642 |
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CAS Registry No. | 1215493-56-3 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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A2205348 | Certificate of Analysis | Oct 10, 2023 | R127721 |
A2205349 | Certificate of Analysis | Oct 10, 2023 | R127721 |
A2205350 | Certificate of Analysis | Oct 10, 2023 | R127721 |
A2205354 | Certificate of Analysis | Oct 10, 2023 | R127721 |
A2205359 | Certificate of Analysis | Oct 10, 2023 | R127721 |
A2205360 | Certificate of Analysis | Oct 10, 2023 | R127721 |
Solubility | insoluble in H2O; ≥16.95 mg/mL in DMSO; ≥8.05 mg/mL in EtOH with gentle warming and ultrasonic |
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1. Rai M, Soragni E, Chou CJ, Barnes G, Jones S, Rusche JR, Gottesfeld JM, Pandolfo M. (2010) Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model.. PLoS ONE, 5 (1): (e8825). [PMID:20098685] |