RGS4 inhibitor 11b , CAS No.410074-60-1, Inhibitor of regulator of G-protein signaling 4;Inhibitor of regulator of G-protein signaling 8

Item Number
R613174
Grouped product items
SKUSizeAvailabilityPrice Qty
R613174-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$271.90
R613174-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$946.90

Basic Description

Synonymsthiadiazolidinone (TDZD) deriv. 6
Specifications & PurityMoligand™
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of regulator of G-protein signaling 4;Inhibitor of regulator of G-protein signaling 8

Associated Targets(Human)

RGS8 Tchem Regulator of G-protein signaling 8 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
RGS4 Tchem Regulator of G-protein signaling 4 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (7750 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS8 Tchem Regulator of G-protein signaling 8 (45 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 4-butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione
INCHI InChI=1S/C8H14N2O2S/c1-3-5-6-9-7(11)10(4-2)13-8(9)12/h3-6H2,1-2H3
InChi Key WTFFYZGCISALRI-UHFFFAOYSA-N
Canonical SMILES CCCCn1c(=O)sn(c1=O)CC
Isomeric SMILES CCCCN1C(=O)N(SC1=O)CC
PubChem CID 6539137

Certificates

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Related Documents

References

1. Turner EM, Blazer LL, Neubig RR, Husbands SM.  (2012)  Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins..  ACS Med Chem Lett,  (2): (146-150).  [PMID:22368763]

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