Rhapontigenin - >96.0%, high purity , CAS No.500-65-2

  • ≥96%
Item Number
R160836
Grouped product items
SKUSizeAvailabilityPrice Qty
R160836-10mg
10mg
In stock
$218.90
R160836-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$492.90
R160836-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,773.90

Potent, selective cytochrome P450 1A1 inhibitor

Basic Description

SynonymsAS-68092 | Forst U 46 | HMS3266N10 | (E)-5-(3-Hydroxy-4-methoxystyryl)benzene-1,3-diol | 22BG4NNH6W | AKOS037515600 | Rhapontin genin | Umdipyridyl | 5-((1E)-2-(3-HYDROXY-4-METHOXYPHENYL)ETHENYL)-1,3-BENZENEDIOL | MFCD00017718 | s9163 | SCHEMBL1486816 | D
Specifications & Purity≥96%
Biochemical and Physiological MechanismsPotent, selective cytochrome P450 1A1 inhibitor (IC 50 = 400 nM). Various pharmacological activities including anticancer, antioxidant, antifungal and antibacterial .
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Rhapontigenin is a natural analog of resveratrol with anticancer, antioxidant, antifungal and antibacterial activities. Rhapontigenin is amechanism-based, potent and selective cytochrome P450 1A1 inactivator (IC50  = 400 nM). Rhapontigenin exhibits 400-fold and 23-fold selectivity for P450 1A1 over P450 1A2 and P450 1B1, respectively

Associated Targets(Human)

MGAM Tclin Maltase-glucoamylase (654 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDA-MB-231 (73002 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
J774 (3120 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 5-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]benzene-1,3-diol
INCHI InChI=1S/C15H14O4/c1-19-15-5-4-10(8-14(15)18)2-3-11-6-12(16)9-13(17)7-11/h2-9,16-18H,1H3/b3-2+
InChi Key PHMHDRYYFAYWEG-NSCUHMNNSA-N
Canonical SMILES COC1=C(C=C(C=C1)C=CC2=CC(=CC(=C2)O)O)O
Isomeric SMILES COC1=C(C=C(C=C1)/C=C/C2=CC(=CC(=C2)O)O)O
PubChem CID 5320954
Molecular Weight 258.27
Reaxy-Rn 2619492

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SensitivityLight sensitive ;Air sensitive ;Heat sensitive
Melt Point(°C)191 °C

Safety and Hazards(GHS)

Reaxy-Rn 2619492

Related Documents

Solution Calculators