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RHC-80267 - ≥98%, high purity , CAS No.83654-05-1, Inhibitor of Diacylglycerol lipase α;Inhibitor of Diacylglycerol lipase β

  • Moligand™
  • ≥98%
Item Number
R274741
Grouped product items
SKUSizeAvailabilityPrice Qty
R274741-10mg
10mg
In stock
$88.90
R274741-25mg
25mg
In stock
$177.90
R274741-50mg
50mg
In stock
$296.90
R274741-250mg
250mg
In stock
$1,336.90

Selective diacylglycerol lipase inhibitor

Basic Description

SynonymsRhc 80267|83654-05-1|RHC-80267|1,6-Bis(cyclohexyloximinocarbonyl)hexane|RHC80267|U 57908|U-57908|1,6-BIS(CYCLOHEXYLOXIMINOCARBONYLAMINO)HEXANE|1,6-Di(O-(carbamoyl)cyclohexanone oxime)hexane|9VB68H5WIT|CHEMBL158897|Cyclohexanone O-((6-((((cyclohexylideneam
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsSelective diacylglycerol lipase inhibitor (IC 50 = 4 μM). Enhances acetylcholine induced smooth muscle relaxation in vitro .
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of Diacylglycerol lipase α;Inhibitor of Diacylglycerol lipase β
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at Room Temperature. The product can be stored for up to 12 months.

Associated Targets

DAGLB Tchem Sn1-specific diacylglycerol lipase beta 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

DAGLA Tchem Sn1-specific diacylglycerol lipase alpha 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KMT2A Tchem Histone-lysine N-methyltransferase 2A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

FAAH Tchem Fatty-acid amide hydrolase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RGS4 Tchem Regulator of G-protein signaling 4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MGLL Tchem Monoglyceride lipase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

LIPE Tchem Hormone-sensitive lipase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ACHE Tclin Acetylcholinesterase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABHD6 Tchem Monoacylglycerol lipase ABHD6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABHD12 Tchem Monoacylglycerol lipase ABHD12 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABHD16A Tchem Protein ABHD16A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PLA2G7 Tchem Platelet-activating factor acetylhydrolase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NCEH1 Tchem Neutral cholesterol ester hydrolase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (cyclohexylideneamino) N-[6-[(cyclohexylideneamino)oxycarbonylamino]hexyl]carbamate
INCHI InChI=1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26)
InChi Key RXSVYGIGWRDVQC-UHFFFAOYSA-N
Canonical SMILES C1CCC(=NOC(=O)NCCCCCCNC(=O)ON=C2CCCCC2)CC1
Isomeric SMILES C1CCC(=NOC(=O)NCCCCCCNC(=O)ON=C2CCCCC2)CC1
PubChem CID 5063
Molecular Weight 394.6

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot NumberCertificate TypeDateItem
H2218507Certificate of AnalysisJun 05, 2023 R274741
H2218510Certificate of AnalysisJun 05, 2023 R274741
H2218511Certificate of AnalysisJun 05, 2023 R274741
H2218509Certificate of AnalysisJun 05, 2023 R274741

Chemical and Physical Properties

SolubilitySoluble in DMSO to 50 mM and in ethanol to 50 mM

Related Documents

Solution Calculators