Rhodamine 123 - 98%, high purity , CAS No.62669-70-9

13 Citations
  • ≥98%
Item Number
R299309
Grouped product items
SKUSizeAvailabilityPrice Qty
R299309-5mg
5mg
In stock
$64.90
R299309-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$116.90
R299309-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$186.90
R299309-500mg
500mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$499.90
View related series
Fluorescent Dye

Basic Description

SynonymsSCHEMBL3808879 | RH-123; R-22420 | RH-123 | rhodamine 110 methyl ester | CS-W012067 | Rhodamine 123, BioReagent, for fluorescence, >=85% (HPLC) | s3577 | F9995-1239 | CHEBI:8828 | RH 123 | 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester monoh
Specifications & Purity≥98%
Biochemical and Physiological MechanismsFluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Functional assays for MDR proteins are better prognostic indicators in cancer therapy than levels of MDR protein expression. Rh 123 can be used in multiparameter analyses
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms

Associated Targets(Human)

A2780 (11979 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCG2 Tchem ATP-binding cassette sub-family G member 2 (4927 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCB11 Tchem Bile salt export pump (2311 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1a P-glycoprotein 3 (492 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Saccharomyces cerevisiae (19171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FM3A (1296 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1 Multidrug resistance protein 1 (79 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABC1 ATP binding cassette transporter Abc1p (50 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name methyl 2-(3-amino-6-iminoxanthen-9-yl)benzoate;hydrochloride
INCHI InChI=1S/C21H16N2O3.ClH/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20;/h2-11,22H,23H2,1H3;1H
InChi Key MYFATKRONKHHQL-UHFFFAOYSA-N
Canonical SMILES COC(=O)C1=CC=CC=C1C2=C3C=CC(=N)C=C3OC4=C2C=CC(=C4)N.Cl
Isomeric SMILES COC(=O)C1=CC=CC=C1C2=C3C=CC(=N)C=C3OC4=C2C=CC(=C4)N.Cl
WGK Germany 3
PubChem CID 9929799
Molecular Weight 380.82
Beilstein 6030951

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
F2411426Certificate of AnalysisMay 27, 2024 R299309
F2411427Certificate of AnalysisMay 27, 2024 R299309
F2411428Certificate of AnalysisMay 27, 2024 R299309
F2411429Certificate of AnalysisMay 27, 2024 R299309
F2411430Certificate of AnalysisMay 27, 2024 R299309
L2318379Certificate of AnalysisNov 23, 2023 R299309
L2318380Certificate of AnalysisNov 23, 2023 R299309
L2318381Certificate of AnalysisNov 23, 2023 R299309
L2318393Certificate of AnalysisNov 23, 2023 R299309
G2219230Certificate of AnalysisJul 22, 2022 R299309

Chemical and Physical Properties

SolubilitySoluble in ethanol (20 mg/ml), DMSO, methanol, and water (partly miscible).
Melt Point(°C)235°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

WGK Germany 3

Related Documents

Citations of This Product

1. Junwei Yao, Heng Zhi, Qingshan Shi, Yu Zhang, Jin Feng, Jingxia Liu, Hui Huang, Xiaobao Xie.  (2023)  Tannic Acid Interfacial Modification of Prochloraz Ethyl Cellulose Nanoparticles for Enhancing the Antimicrobial Effect and Biosafety of Fungicides.  ACS Applied Materials & Interfaces,  15  (35): (41324–41336).  [PMID:37602737]
2. He Yan, Li Junjie, Yi Liling, Li Xiaohuan, Luo Man, Pang Yayan, Wang Maoju, Li Zhaolun, Xu Mingliang, Dong Zhifang, Du Yehong.  (2023)  Octadecaneuropeptide Ameliorates Cognitive Impairments Through Inhibiting Oxidative Stress in Alzheimer’s Disease Models.  JOURNAL OF ALZHEIMERS DISEASE,  92  (4): (1413-1426).  [PMID:36911940]
3. Ruiyu Zhu, Weilun Wang, Zisheng Luo, Haiyan Lin, Yong Li, Weiqiang Lu, Zimu Xu, Chenggang Cai, Shuheng Hu.  (2023)  Blue LED light treatment inhibits virulence and patulin biosynthesis in Penicillium expansum.  POSTHARVEST BIOLOGY AND TECHNOLOGY,  200  (112340).  [PMID:]
4. Yu Le, Wang Zhuang, Wang De-Gao.  (2023)  Factors affecting the toxicity and oxidative stress of layered double hydroxide-based nanomaterials in freshwater algae.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  30  (22): (63109-63120).  [PMID:36959400]
5. Xiaomei Liang, Yulu Yang, Chuanqing Huang, Zhibin Ye, Wujiang Lai, Jiamao Luo, Xiaoxuan Li, Xiao Yi, Jun-Bing Fan, Ying Wang, Yifeng Wang.  (2023)  cRGD-targeted heparin nanoparticles for effective dual drug treatment of cisplatin-resistant ovarian cancer.  JOURNAL OF CONTROLLED RELEASE,  356  (691).  [PMID:36933699]
6. Jiali Qian, Hongli Li, Yuanhang Wang, Yixuan Li, Jie Yu, Lei Zhou, Qiaosheng Pu.  (2023)  Zwitterionic surfactant as an additive for efficient electrophoretic separation of easily absorbed rhodamine dyes on plastic microchips.  JOURNAL OF CHROMATOGRAPHY A,  1688  (463716).  [PMID:36565653]
7. Ge Jian, Xu Wei-jia, Chen Hai-feng, Dong Zong-hua, Liu Wei, Nian Fu-zhao, Liu Jun.  (2022)  Induction mechanism of cigarette smoke components (CSCs) on dyslipidemia and hepatic steatosis in rats.  Lipids in Health and Disease,  21  (1): (1-20).  [PMID:36348421]
8. Xinyang Zhang, Zhendong Gan, Yanrui Wang, Xiaobin Tang, Guibai Li, Heng Liang.  (2022)  Effect of chemical cleaning on nanofiltration process in treating surface water.  Journal of Water Process Engineering,  50  (103271).  [PMID:]
9. Bin Zhao, Lixuan Xu, Peixin Shen, Liang Wang, Yiran Qian, Xiaojia He, Xiuru Chu, Pengda Zhang.  (2023)  Effect of fulvic acid on transparent exopolymer particle formation and membrane fouling.  SEPARATION AND PURIFICATION TECHNOLOGY,  305  (122369).  [PMID:]
10. Cong Xu, Jiage Ma, Zhijing Liu, Wan Wang, Xin Liu, Shanshan Qian, Lijun Chen, Liya Gu, Chuanqiang Sun, Juncai Hou, Zhanmei Jiang.  (2023)  Preparation of shell-core fiber-encapsulated Lactobacillus rhamnosus 1.0320 using coaxial electrospinning.  FOOD CHEMISTRY,  402  (134253).  [PMID:36162172]
11. Zhang Ye, Lun Gao, Jiayang Cai, Yixuan Wang, Yong Li, Shiao Tong, Tengfeng Yan, Qian Sun, Yangzhi Qi, Yang Xu, Hongxiang Jiang, Si Zhang, Linyao Zhao, Shenqi Zhang, Qianxue Chen.  (2022)  Esterase-responsive and size-optimized prodrug nanoparticles for effective intracranial drug delivery and glioblastoma treatment.  Nanomedicine-Nanotechnology Biology and Medicine,  44  (102581).  [PMID:35811067]
12. Bingjie Liu, Xinshuo Wang, Lin Lu, Quan Wen, Xiaoming Zhang, Caleb John Swing, Shuqin Xia.  (2022)  Tannic acid modulated the wall compactness of cinnamaldehyde-loaded microcapsules and enhanced inhibitory effect on Aspergillus brasiliensis.  INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY,  57  (8): (5357-5365).  [PMID:]
13. Shanshan Tie, Siyuan Xiang, Yannan Chen, Fengzhi Qiao, Weina Cui, Wentao Su, Mingqian Tan.  (2022)  Facile synthesis of food-grade and size-controlled nanocarriers based on self-assembly of procyanidins and phycocyanin.  Food & Function,  13  (7): (4023-4031).  [PMID:35315469]

References

1. Junwei Yao, Heng Zhi, Qingshan Shi, Yu Zhang, Jin Feng, Jingxia Liu, Hui Huang, Xiaobao Xie.  (2023)  Tannic Acid Interfacial Modification of Prochloraz Ethyl Cellulose Nanoparticles for Enhancing the Antimicrobial Effect and Biosafety of Fungicides.  ACS Applied Materials & Interfaces,  15  (35): (41324–41336).  [PMID:37602737]
2. He Yan, Li Junjie, Yi Liling, Li Xiaohuan, Luo Man, Pang Yayan, Wang Maoju, Li Zhaolun, Xu Mingliang, Dong Zhifang, Du Yehong.  (2023)  Octadecaneuropeptide Ameliorates Cognitive Impairments Through Inhibiting Oxidative Stress in Alzheimer’s Disease Models.  JOURNAL OF ALZHEIMERS DISEASE,  92  (4): (1413-1426).  [PMID:36911940]
3. Ruiyu Zhu, Weilun Wang, Zisheng Luo, Haiyan Lin, Yong Li, Weiqiang Lu, Zimu Xu, Chenggang Cai, Shuheng Hu.  (2023)  Blue LED light treatment inhibits virulence and patulin biosynthesis in Penicillium expansum.  POSTHARVEST BIOLOGY AND TECHNOLOGY,  200  (112340).  [PMID:]
4. Yu Le, Wang Zhuang, Wang De-Gao.  (2023)  Factors affecting the toxicity and oxidative stress of layered double hydroxide-based nanomaterials in freshwater algae.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  30  (22): (63109-63120).  [PMID:36959400]
5. Xiaomei Liang, Yulu Yang, Chuanqing Huang, Zhibin Ye, Wujiang Lai, Jiamao Luo, Xiaoxuan Li, Xiao Yi, Jun-Bing Fan, Ying Wang, Yifeng Wang.  (2023)  cRGD-targeted heparin nanoparticles for effective dual drug treatment of cisplatin-resistant ovarian cancer.  JOURNAL OF CONTROLLED RELEASE,  356  (691).  [PMID:36933699]
6. Jiali Qian, Hongli Li, Yuanhang Wang, Yixuan Li, Jie Yu, Lei Zhou, Qiaosheng Pu.  (2023)  Zwitterionic surfactant as an additive for efficient electrophoretic separation of easily absorbed rhodamine dyes on plastic microchips.  JOURNAL OF CHROMATOGRAPHY A,  1688  (463716).  [PMID:36565653]
7. Ge Jian, Xu Wei-jia, Chen Hai-feng, Dong Zong-hua, Liu Wei, Nian Fu-zhao, Liu Jun.  (2022)  Induction mechanism of cigarette smoke components (CSCs) on dyslipidemia and hepatic steatosis in rats.  Lipids in Health and Disease,  21  (1): (1-20).  [PMID:36348421]
8. Xinyang Zhang, Zhendong Gan, Yanrui Wang, Xiaobin Tang, Guibai Li, Heng Liang.  (2022)  Effect of chemical cleaning on nanofiltration process in treating surface water.  Journal of Water Process Engineering,  50  (103271).  [PMID:]
9. Bin Zhao, Lixuan Xu, Peixin Shen, Liang Wang, Yiran Qian, Xiaojia He, Xiuru Chu, Pengda Zhang.  (2023)  Effect of fulvic acid on transparent exopolymer particle formation and membrane fouling.  SEPARATION AND PURIFICATION TECHNOLOGY,  305  (122369).  [PMID:]
10. Cong Xu, Jiage Ma, Zhijing Liu, Wan Wang, Xin Liu, Shanshan Qian, Lijun Chen, Liya Gu, Chuanqiang Sun, Juncai Hou, Zhanmei Jiang.  (2023)  Preparation of shell-core fiber-encapsulated Lactobacillus rhamnosus 1.0320 using coaxial electrospinning.  FOOD CHEMISTRY,  402  (134253).  [PMID:36162172]
11. Zhang Ye, Lun Gao, Jiayang Cai, Yixuan Wang, Yong Li, Shiao Tong, Tengfeng Yan, Qian Sun, Yangzhi Qi, Yang Xu, Hongxiang Jiang, Si Zhang, Linyao Zhao, Shenqi Zhang, Qianxue Chen.  (2022)  Esterase-responsive and size-optimized prodrug nanoparticles for effective intracranial drug delivery and glioblastoma treatment.  Nanomedicine-Nanotechnology Biology and Medicine,  44  (102581).  [PMID:35811067]
12. Bingjie Liu, Xinshuo Wang, Lin Lu, Quan Wen, Xiaoming Zhang, Caleb John Swing, Shuqin Xia.  (2022)  Tannic acid modulated the wall compactness of cinnamaldehyde-loaded microcapsules and enhanced inhibitory effect on Aspergillus brasiliensis.  INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY,  57  (8): (5357-5365).  [PMID:]
13. Shanshan Tie, Siyuan Xiang, Yannan Chen, Fengzhi Qiao, Weina Cui, Wentao Su, Mingqian Tan.  (2022)  Facile synthesis of food-grade and size-controlled nanocarriers based on self-assembly of procyanidins and phycocyanin.  Food & Function,  13  (7): (4023-4031).  [PMID:35315469]

Solution Calculators