Rhodamine 123 - 10mM in DMSO, high purity , CAS No.62669-70-9

Item Number

R425180

• Synonyms: Rhodamine 123|62669-70-9|rhodamine 110 methyl ester|Rhodamine-123|1N3CZ14C5O|RH 123|methyl 2-(6-amino-3-imino-3H-xanthen-9-yl)benzoate hydrochloride|RH-123;R-22420|Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride|Xanthylium, 3,6-diamino-9-
• Specifications & Purity: 10mM in DMSO
• Biochemical and Physiological Mechanisms: Fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Functional assays for MDR proteins are better prognostic indicators in cancer therapy than levels of MDR protein expression. Rh 123 can be used in multiparameter analyses
• Storage Temp: Store at -80°C
• Shipped In: Ice chest + Ice pads

Product Description

Rhodamine 123 is a cationic dye that emits a green fluorescence. Research observations indicate that Rhodamine 123 can be used to probe the electrochemical gradient in mitochondria, in flow cytometry to detect the activity of P-glycoprotein efflux, and as a compound for P-GP mediating transport. Studies report that Rhodamine 123 can decrease the clonal growth of carcinoma cells in vitro, and that it can associate with placental P-gp. Rhodamine 123 is a substrate of Mdr (P-glycoprotein). Rhodamine 123 is a substrate of MRP1.