Basic Description

Synonyms	Photrexa \| Riboflavine-5'-phosphate sodium \| FLAVIN MONONUCLEOTIDE MONOSODIUM SALT [MI] \| NSC 759230 \| Riboflavina 5 fosfato de sodio \| Riboflavin 5'-(dihydrogen phosphate), sodium salt (1:1) \| Riboflavin monophosphate monosodium salt \| W-108348 \| MFCD000
Specifications & Purity	Ph.Eur.
Biochemical and Physiological Mechanisms	Riboflavin 5′-monophosphate or flavin mononucleotide (FMN) possesses fluorescence, photosensitivity and redox activities.
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Ph.Eur.
Product Description	General Description Riboflavin 5′-monophosphate is also known as flavin mononucleotide (FMN). FMN is a water-soluble micronutrient. It is enzymatically produced from riboflavin (RF). Riboflavin 5′-monophosphate is one of the constituent of enzyme cofactor flavin-adenine dinucleotide. Application Riboflavin 5′-monophosphate sodium salt was used as water-soluble model drug in a combined conventional inkjet printing technology with flexographic printing for the fabrication of drug delivery systems. It may be employed as initiator for the photo-initiated polymerization of acrylamide. It may be employed in chronoamperometric assay for vanadium ions.

Associated Targets(Human)

TST Tchem Thiosulfate sulfurtransferase (0 Activities)

Discover Target: TST

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	sodium;[(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate
INCHI	InChI=1S/C17H21N4O9P.Na/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29;/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29);/q;+1/p-1/t11-,12+,14-;/m0./s1
InChi Key	OHSHFZJLPYLRIP-BMZHGHOISA-M
Canonical SMILES	CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)[O-])O)O)O.[Na+]
Isomeric SMILES	CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C[C@@H]([C@@H]([C@@H](COP(=O)(O)[O-])O)O)O.[Na+]
WGK Germany	3
PubChem CID	23666409
Molecular Weight	478.33
Beilstein	4106529

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility	water: soluble 100g/L at20°C
Specific Rotation[α]	41 ° (C=1.5, 5mol/L HCl)

Safety and Hazards(GHS)

WGK Germany	3
Merck Index	8201

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jianmin Chen,Yuqin Qiu,Suohui Zhang,Guozhong Yang,Yunhua Gao. (2014-01-01) Controllable coating of microneedles for transdermal drug delivery.. Drug development and industrial pharmacy, 41 ((3)): (415-422). [PMID:24378200]
2. Shihui Qiu, Yue Yu, Yun-Han Chang, Lei Shan, Shoufang Xu. (2024) Nonconductive layered hexagonal boron nitride preparation via a co-exfoliation strategy and nanohybrid coating construction for corrosion protection. PROGRESS IN ORGANIC COATINGS, 186 (108052). [PMID:26794871] [10.1016/j.porgcoat.2023.108052]
3. Guangdong Sun, Xiuling He, Meilin Feng, Xia Xu, Jine Chen, Yongqiang Wang. (2023) Flavin mononucleotide in visible light photoinitiating systems for multiple-photocrosslinking and photoencapsulation strategies. Acta Biomaterialia, 172 (22): (272). [PMID:37797710] [10.1016/j.actbio.2023.09.051]
4. Lei Jiafeng, Zhang Yaqin, Yao Yanxin, Shi Yang, Leung Ka Lok, Fan Jun, Lu Yi-Chun. (2023) An active and durable molecular catalyst for aqueous polysulfide-based redox flow batteries. Nature Energy, (19): (1-10). [PMID:14699141] [10.1038/s41560-023-01370-0]
5. Gangying Feng, Shitong Zhang, Shuangling Zhong, Miao Tan, Yongyan Yang, Yueming Dou, Xuejun Cui. (2021) Temperature and pH dual-responsive supramolecular hydrogels based on riboflavin sodium phosphate and 2,6-Diaminopurine with thixotropic and fluorescent properties. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 630 (127548). [PMID:] [10.1016/j.colsurfa.2021.127548]
6. Yue Lang, Yanan Yu, Hongtao Zou, Jiexu Ye, Shihan Zhang, Jianmeng Chen. (2022) Flavin mononucleotide-stimulated microbial fuel cell for efficient gaseous toluene abatement. CHEMOSPHERE, 287 (132247). [PMID:34826930] [10.1016/j.chemosphere.2021.132247]
7. Gabriel Sikukuu Nambafu, Kumar Siddharth, Cheng Zhang, Tianshou Zhao, Qing Chen, Khalil Amine, Minhua Shao. (2021) An organic bifunctional redox active material for symmetric aqueous redox flow battery. Nano Energy, 89 (106422). [PMID:] [10.1016/j.nanoen.2021.106422]
8. Jingyi Liu, Shuhua Han, Yongfeng Hu, Chih-Wen Pao. (2021) Fabrication and characterization of a novel PMO containing riboflavin-5'-phosphate sodium salt for sensitive detection of pesticide ferbam. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 617 (126375). [PMID:] [10.1016/j.colsurfa.2021.126375]
9. Chenxi Yu, Wenyu Zhu, Zhaozhan He, Jin Xu, Fengyan Fang, Ziang Gao, Wenli Ding, Yixiang Wang, Jing Wang, Junqiao Wang, Ao Huang, Aohua Cheng, Yanhui Wei, Shiyun Ai. (2021) ATP-triggered drug release system based on ZIF-90 loaded porous poly(lactic-co-glycolic acid) microspheres. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 615 (126255). [PMID:] [10.1016/j.colsurfa.2021.126255]
10. Junli Guo, Lingling Yang, Zhida Gao, Chenxi Zhao, Ye Mei, Yan-Yan Song. (2020) Insight of MOF Environment-Dependent Enzyme Activity via MOFs-in-Nanochannels Configuration. ACS Catalysis, 10 (10): (5949–5958). [PMID:] [10.1021/acscatal.0c00591]
11. Chunning Heng, Xiaoyan Zheng, Meiying Liu, Dazhuang Xu, Hongye Huang, Fengjie Deng, Junfeng Hui, Xiaoyong Zhang, Yen Wei. (2016) Fabrication of luminescent hydroxyapatite nanorods through surface-initiated RAFT polymerization: Characterization, biological imaging and drug delivery applications. APPLIED SURFACE SCIENCE, 386 (269). [PMID:] [10.1016/j.apsusc.2016.05.157]
12. Zhixiong Li, Ruizheng Liang, Wendi Liu, Dongpeng Yan, Min Wei. (2015) A dual-stimuli-responsive fluorescent switch ultrathin film. Nanoscale, 7 (40): (16737-16743). [PMID:26400734] [10.1039/C5NR05376E]
13. Jiang Wu, Ying Liu, Wei Li, Chunyan Wang, Yanjun Li, Ying Tian, Jing Sun, Shouju Wang, Xin Wang, Yuxia Tang, Hong Zhu, Zhaogang Teng, Guangming Lu. (2014) Magnetically guided survivin-siRNA delivery and simultaneous dual-modal imaging visualization based on Fe3O4@mTiO2 nanospheres for breast cancer. Journal of Materials Chemistry B, 2 (44): (7756-7764). [PMID:32261912] [10.1039/C4TB01264J]

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37. Guangdong Sun, Xiuling He, Meilin Feng, Xia Xu, Jine Chen, Yongqiang Wang. (2023) Flavin mononucleotide in visible light photoinitiating systems for multiple-photocrosslinking and photoencapsulation strategies. Acta Biomaterialia, 172 (22): (272). [PMID:37797710] [10.1016/j.actbio.2023.09.051]
38. Lei Jiafeng, Zhang Yaqin, Yao Yanxin, Shi Yang, Leung Ka Lok, Fan Jun, Lu Yi-Chun. (2023) An active and durable molecular catalyst for aqueous polysulfide-based redox flow batteries. Nature Energy, (19): (1-10). [PMID:14699141] [10.1038/s41560-023-01370-0]
39. Gangying Feng, Shitong Zhang, Shuangling Zhong, Miao Tan, Yongyan Yang, Yueming Dou, Xuejun Cui. (2021) Temperature and pH dual-responsive supramolecular hydrogels based on riboflavin sodium phosphate and 2,6-Diaminopurine with thixotropic and fluorescent properties. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 630 (127548). [PMID:] [10.1016/j.colsurfa.2021.127548]
40. Yue Lang, Yanan Yu, Hongtao Zou, Jiexu Ye, Shihan Zhang, Jianmeng Chen. (2022) Flavin mononucleotide-stimulated microbial fuel cell for efficient gaseous toluene abatement. CHEMOSPHERE, 287 (132247). [PMID:34826930] [10.1016/j.chemosphere.2021.132247]
41. Gabriel Sikukuu Nambafu, Kumar Siddharth, Cheng Zhang, Tianshou Zhao, Qing Chen, Khalil Amine, Minhua Shao. (2021) An organic bifunctional redox active material for symmetric aqueous redox flow battery. Nano Energy, 89 (106422). [PMID:] [10.1016/j.nanoen.2021.106422]
42. Jingyi Liu, Shuhua Han, Yongfeng Hu, Chih-Wen Pao. (2021) Fabrication and characterization of a novel PMO containing riboflavin-5'-phosphate sodium salt for sensitive detection of pesticide ferbam. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 617 (126375). [PMID:] [10.1016/j.colsurfa.2021.126375]
43. Chenxi Yu, Wenyu Zhu, Zhaozhan He, Jin Xu, Fengyan Fang, Ziang Gao, Wenli Ding, Yixiang Wang, Jing Wang, Junqiao Wang, Ao Huang, Aohua Cheng, Yanhui Wei, Shiyun Ai. (2021) ATP-triggered drug release system based on ZIF-90 loaded porous poly(lactic-co-glycolic acid) microspheres. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 615 (126255). [PMID:] [10.1016/j.colsurfa.2021.126255]
44. Junli Guo, Lingling Yang, Zhida Gao, Chenxi Zhao, Ye Mei, Yan-Yan Song. (2020) Insight of MOF Environment-Dependent Enzyme Activity via MOFs-in-Nanochannels Configuration. ACS Catalysis, 10 (10): (5949–5958). [PMID:] [10.1021/acscatal.0c00591]
45. Chunning Heng, Xiaoyan Zheng, Meiying Liu, Dazhuang Xu, Hongye Huang, Fengjie Deng, Junfeng Hui, Xiaoyong Zhang, Yen Wei. (2016) Fabrication of luminescent hydroxyapatite nanorods through surface-initiated RAFT polymerization: Characterization, biological imaging and drug delivery applications. APPLIED SURFACE SCIENCE, 386 (269). [PMID:] [10.1016/j.apsusc.2016.05.157]
46. Zhixiong Li, Ruizheng Liang, Wendi Liu, Dongpeng Yan, Min Wei. (2015) A dual-stimuli-responsive fluorescent switch ultrathin film. Nanoscale, 7 (40): (16737-16743). [PMID:26400734] [10.1039/C5NR05376E]
47. Jiang Wu, Ying Liu, Wei Li, Chunyan Wang, Yanjun Li, Ying Tian, Jing Sun, Shouju Wang, Xin Wang, Yuxia Tang, Hong Zhu, Zhaogang Teng, Guangming Lu. (2014) Magnetically guided survivin-siRNA delivery and simultaneous dual-modal imaging visualization based on Fe3O4@mTiO2 nanospheres for breast cancer. Journal of Materials Chemistry B, 2 (44): (7756-7764). [PMID:32261912] [10.1039/C4TB01264J]

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Riboflavin 5′-monophosphate sodium salt - tested according to Ph. Eur., high purity , CAS No.130-40-5