Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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R126176-250mg | 250mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $31.90 | |
R126176-1g | 1g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $103.90 | |
R126176-5g | 5g | In stock | $414.90 | |
R126176-25g | 25g | In stock | $1,867.90 |
Broad spectrum antibiotic. Active against gram-positive and gram-negative bacteria.
Synonyms | Rifaximin | Rifaxidin | Rifacol | Rifamycin L 105 | 80621-81-4 | Xifaxan | Fatroximin | Rifaximine | Normix | Rifamycin L 105SV | Rifaximina | Rifamixin | Ritacol | Rifaximinum | Xifaxsan | Rifaximinum [Latin] | Rifaxin | rifaximinun | L-105 | L 105SV | L 105 (Ansamacrolide antibiotic) | Rifaximi |
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Specifications & Purity | Moligand™, ≥97% |
Biochemical and Physiological Mechanisms | Rifaximin is an antibiotic that inhibits RNA synthesis and acts as a PXR (pregnane-X-receptor) activator. The compound is a derivative of rifamycin that has been shown to act strongly against Enterococcus, Streptococcus and Staphylococcus, with less activ |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Rifaximin, an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. |
ALogP | 6.9 |
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IUPAC Name | [(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,36-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22,30-octamethyl-6,23-dioxo-8,37-dioxa-24,27,33-triazahexacyclo[23.10.1.14,7.05,35.026,34.027,32]heptatriaconta-1(35),2,4,9,19,21,25(36),26(34),28,30,32-undecaen-13-yl] acetate |
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INCHI | InChI=1S/C43H51N3O11/c1-19-14-16-46-28(18-19)44-32-29-30-37(50)25(7)40-31(29)41(52)43(9,57-40)55-17-15-27(54-10)22(4)39(56-26(8)47)24(6)36(49)23(5)35(48)20(2)12-11-13-21(3)42(53)45-33(34(32)46)38(30)51/h11-18,20,22-24,27,35-36,39,48-51H,1-10H3,(H,45,53)/b12-11+,17-15+,21-13-/t20-,22+,23+,24+,27-,35-,36+,39+,43-/m0/s1 |
InChi Key | NZCRJKRKKOLAOJ-XRCRFVBUSA-N |
Canonical SMILES | CC1C=CC=C(C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C5=C2N6C=CC(=CC6=N5)C)O)C |
Isomeric SMILES | C[C@H]1/C=C/C=C(\C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)O[C@@](C4=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C5=C2N6C=CC(=CC6=N5)C)O)/C |
PubChem CID | 6436173 |
Molecular Weight | 785.88 |
CAS Registry No. | 80621-81-4 |
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PubChem CID | 6436173 |
ChEMBL Ligand | CHEMBL1617 |
Wikipedia | Rifaximin |
ChEBI | CHEBI:75246 |
DrugBank Ligand | DB01220 |
RCSB PDB Ligand | RXM |
Antibiotic DB | 1859 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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E2413050 | Certificate of Analysis | May 16, 2024 | R126176 |
E2220140 | Certificate of Analysis | Mar 14, 2024 | R126176 |
E2220147 | Certificate of Analysis | Mar 14, 2024 | R126176 |
C2004053 | Certificate of Analysis | Oct 18, 2023 | R126176 |
Solubility | Soluble in DMSO (47 mg/ml), water (<1 mg/ml), ethanol (157 mg/ml), alcohols, and chloroform. |
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Sensitivity | Heat sensitive |
Melt Point(°C) | 212 °C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H335:May cause respiratory irritation H312:Harmful in contact with skin H332:Harmful if inhaled H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P319:Get medical help if you feel unwell. |
Merck Index | 8220 |
1. Lei Wang, Jinyan Lei, Zeyu Zhao, Jianwei Jia, Li Wang. (2023) Therapeutic effects of paeoniflorin on irritable bowel syndrome in rats. Journal of Veterinary Science, 24 (3): ( e23). [PMID:37271501] |
2. Xin Meng, Ye Wang. (2021) Drug Repurposing for Influenza Virus Polymerase Acidic (PA) Endonuclease Inhibitor. MOLECULES, 26 (23): (7326). [PMID:34885905] |
1. Gomi H, Jiang ZD, Adachi JA, Ashley D, Lowe B, Verenkar MP, Steffen R, DuPont HL. (2001) In vitro antimicrobial susceptibility testing of bacterial enteropathogens causing traveler's diarrhea in four geographic regions.. Antimicrob Agents Chemother, 45 (1): (212-6). [PMID:11120968] |
2. Brufani M, Cellai L, Cerrini S, Fedeli W, Marchi E, Segre A, Vaciago A. (1984) X-ray crystal structure of 4-deoxy-3'-bromopyrido[1',2'-1,2]imidazo[5,4-c]rifamycin S.. J Antibiot (Tokyo), 37 (12): (1623-7). [PMID:6549316] |
3. Hoover WW, Gerlach EH, Hoban DJ, Eliopoulos GM, Pfaller MA, Jones RN. (1993) Antimicrobial activity and spectrum of rifaximin, a new topical rifamycin derivative.. Diagn Microbiol Infect Dis, 16 (2): (111-8). [PMID:8385592] |
4. Lei Wang, Jinyan Lei, Zeyu Zhao, Jianwei Jia, Li Wang. (2023) Therapeutic effects of paeoniflorin on irritable bowel syndrome in rats. Journal of Veterinary Science, 24 (3): ( e23). [PMID:37271501] |
5. Xin Meng, Ye Wang. (2021) Drug Repurposing for Influenza Virus Polymerase Acidic (PA) Endonuclease Inhibitor. MOLECULES, 26 (23): (7326). [PMID:34885905] |