Rimonabant - ≥98%, high purity , Cannabinoid CB1 receptor antagonist, CAS No.168273-06-1, Cannabinoid CB1 receptor antagonist

Item Number

R125003

• Synonyms: 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide | s3021 | (N-(Piperidin-1-yl)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide | 158681-13-1 (HCl) | AY6 | BR164345 | GTPL743 | SB19549 | W-108076 | 1H-Py
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: Rimonabant, also known as SR141716, was the first selective CB1 (cannabinoid 1) central receptor inverse agonist (Ki = 1.8 nM). It is widely used as a tool to investigate CB receptor properties and the mechanisms by which CB agonists exert their pharmacol
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Action Type: ANTAGONIST
• Mechanism of action: Cannabinoid CB1 receptor antagonist
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane.
An immunomodulatory CB1 receptor inverse agonist.