RIPK1-IN-4 - 98%, high purity , CAS No.1481641-08-0

Item Number

R648090

Grouped product items
SKU	Size	Availability	Price
R648090-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$150.90
R648090-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$350.90
R648090-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$550.90
R648090-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$990.90
R648090-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,650.90
R648090-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,250.90

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Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC 50 s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC 50 s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase Form:Solid IC50& Target:IC50: 16 nM (RIP1) and 10 nM (ADP-Glo)

Names and Identifiers

IUPAC Name	1-[4-(1-aminoisoquinolin-5-yl)phenyl]-3-(5-tert-butyl-1,2-oxazol-3-yl)urea
INCHI	InChI=1S/C23H23N5O2/c1-23(2,3)19-13-20(28-30-19)27-22(29)26-15-9-7-14(8-10-15)16-5-4-6-18-17(16)11-12-25-21(18)24/h4-13H,1-3H3,(H2,24,25)(H2,26,27,28,29)
InChi Key	SLRYMOUSQMDJPH-UHFFFAOYSA-N
Canonical SMILES	CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CC=CC4=C3C=CN=C4N
Isomeric SMILES	CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CC=CC4=C3C=CN=C4N
PubChem CID	71816195
Molecular Weight	401.46

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Basic Description