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Rivastigmine - ≥99%, high purity , Cholinesterases; ACHE & BCHE inhibitor, CAS No.123441-03-2, Cholinesterases; ACHE & BCHE inhibitor
Basic Description
| Synonyms | AC-8250 | rivastigmine hexal | Rivastigmine impurity D | SR-05000001475 | SR-05000001475-2 | BDBM10620 | Carbamic acid, ethylmethyl-, 3-((1S)-1-(dimethylamino)ethyl)phenyl ester | DTXCID703564 | ONO-2540 | Rivastigmina | Rivastigmine sandoz | W-200966 | R |
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| Specifications & Purity | Moligand™, ≥99% |
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| Storage Temp | Store at 2-8°C,Argon charged |
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| Shipped In | Wet ice |
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| Grade | Moligand™ |
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| Action Type | INHIBITOR |
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| Mechanism of action | Cholinesterases; ACHE & BCHE inhibitor |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | [3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate |
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| INCHI | InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 |
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| InChi Key | XSVMFMHYUFZWBK-NSHDSACASA-N |
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| Canonical SMILES | CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C |
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| Isomeric SMILES | CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C |
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| PubChem CID | 77991 |
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| Molecular Weight | 250.34 |
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Chemical and Physical Properties
| Solubility | Soluble in methanol and ethanol |
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| Sensitivity | light sensitive |
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| Flash Point(°C) | 145.0 °C |
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| Boil Point(°C) | 135 °C/0.26 mmHg |
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Citations of This Product
| 1. Jieqing Feng, Qisheng Zhong, Ting Zhou. (2022) Online Pressure Change Focusing-Supercritical Fluid Selective Extraction Chromatography for Analyzing Chiral Drugs in Microliter-Scale Plasma Samples. ANALYTICAL CHEMISTRY, 94 (46): (16222–16230). [PMID:36356211] [10.1021/acs.analchem.2c03892] |
References
| 1. Birks J, McGuinness B, Craig D. (2013) Rivastigmine for vascular cognitive impairment.. Cochrane Database Syst Rev, 5 (13): (CD004744). [PMID:23728651] [10.1021/op500134e] |
| 2. Jieqing Feng, Qisheng Zhong, Ting Zhou. (2022) Online Pressure Change Focusing-Supercritical Fluid Selective Extraction Chromatography for Analyzing Chiral Drugs in Microliter-Scale Plasma Samples. ANALYTICAL CHEMISTRY, 94 (46): (16222–16230). [PMID:36356211] [10.1021/acs.analchem.2c03892] |
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