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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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R129987-250mg | 250mg | In stock | $46.90 | |
R129987-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $142.90 | |
R129987-5g | 5g | In stock | $495.90 |
Acetylcholinesterase and butyrylcholinesterase inhibitor
Synonyms | Q27133236 | AKOS022179413 | AS-14385 | AKOS003617905 | Carbamic acid, ethylmethyl-, 3-(1-(dimethylamino)ethyl)phenyl ester, (S)-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1) | HMS3884H05 | HMS3678F17 | SDZ-ENA 713 | ENA 713 | perfluoro-n-octanesulfonic ac |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Rivastigmine hydrogen tartrate is a parasympathomimetic or cholinergic agent. Rivastigmine hydrogen tartrate is also a dual ChEI (cholinesterase inhibitor); inhibiting BChE (butyrylcholinesterase) and AChE (acetylcholinesterase).Acetylcholinesterase and b |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Action Type | INHIBITOR |
Mechanism of action | Cholinesterases; ACHE & BCHE inhibitor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Rivastigmine Tartrate is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (2R,3R)-2,3-dihydroxybutanedioic acid;[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate |
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INCHI | InChI=1S/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m01/s1 |
InChi Key | GWHQHAUAXRMMOT-MBANBULQSA-N |
Canonical SMILES | CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.C(C(C(=O)O)O)(C(=O)O)O |
Isomeric SMILES | CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O |
WGK Germany | 3 |
RTECS | FA9550000 |
PubChem CID | 6918078 |
Molecular Weight | 400.42 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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F1501131 | Certificate of Analysis | Jan 06, 2023 | R129987 |
K2229795 | Certificate of Analysis | Dec 09, 2022 | R129987 |
F2216222 | Certificate of Analysis | Jun 21, 2022 | R129987 |
F2216220 | Certificate of Analysis | Jun 20, 2022 | R129987 |
F2216221 | Certificate of Analysis | Jun 20, 2022 | R129987 |
Solubility | DMSO 42 mg/mL Water 80 mg/mL Ethanol 80 mg/mL |
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Specific Rotation[α] | 5° (C=5,MeOH) |
Melt Point(°C) | 126 °C |
WGK Germany | 3 |
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RTECS | FA9550000 |