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RJW100 , CAS No.R613213, Agonist of Liver receptor homolog-1;Agonist of Steroidogenic factor 1
Basic Description
Synonyms | 24-exo |
Specifications & Purity | Moligand™ |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of Liver receptor homolog-1;Agonist of Steroidogenic factor 1 |
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Associated Targets(Human)
Names and Identifiers
IUPAC Name | rac-(1R,5R,6R)-3-Hexyl-6-hydroxy-2-phenyl-1-(phenylvinyl)-bicyclo[3.3.0]oct-2-ene |
INCHI | InChI=1S/C28H34O/c1-3-4-5-8-17-24-20-25-26(29)18-19-28(25,21(2)22-13-9-6-10-14-22)27(24)23-15-11-7-12-16-23/h6-7,9-16,25-26,29H,2-5,8,17-20H2,1H3/t25?,26-,28+/m1/s1 |
InChi Key | ZFXMYHPLTQTTFW-XZSHQJGLSA-N |
Canonical SMILES | CCCCCCC1=C(c2ccccc2)[C@]2(C(C1)[C@H](O)CC2)C(=C)c1ccccc1 |
Isomeric SMILES | CCCCCCC1=C([C@@]2(CC[C@H](C2C1)O)C(=C)C3=CC=CC=C3)C4=CC=CC=C4 |
PubChem CID | 139030533 |
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References
1. Whitby RJ, Stec J, Blind RD, Dixon S, Leesnitzer LM, Orband-Miller LA, Williams SP, Willson TM, Xu R, Zuercher WJ et al.. (2011) Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2).. J Med Chem, 54 (7): (2266-81). [PMID:21391689] |
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