RJW100 , CAS No.R613213, Agonist of Liver receptor homolog-1;Agonist of Steroidogenic factor 1

Item Number
R613213
Grouped product items
SKUSizeAvailabilityPrice Qty
R613213-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,068.90
R613213-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,738.90

Basic Description

Synonyms24-exo
Specifications & PurityMoligand™
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of Liver receptor homolog-1;Agonist of Steroidogenic factor 1

Associated Targets(Human)

NR5A1 Tchem Steroidogenic factor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR5A2 Tchem Nuclear receptor subfamily 5 group A member 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NR5A2 Tchem Orphan nuclear receptor LRH-1 (736 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name rac-(1R,5R,6R)-3-Hexyl-6-hydroxy-2-phenyl-1-(phenylvinyl)-bicyclo[3.3.0]oct-2-ene
INCHI InChI=1S/C28H34O/c1-3-4-5-8-17-24-20-25-26(29)18-19-28(25,21(2)22-13-9-6-10-14-22)27(24)23-15-11-7-12-16-23/h6-7,9-16,25-26,29H,2-5,8,17-20H2,1H3/t25?,26-,28+/m1/s1
InChi Key ZFXMYHPLTQTTFW-XZSHQJGLSA-N
Canonical SMILES CCCCCCC1=C(c2ccccc2)[C@]2(C(C1)[C@H](O)CC2)C(=C)c1ccccc1
Isomeric SMILES CCCCCCC1=C([C@@]2(CC[C@H](C2C1)O)C(=C)C3=CC=CC=C3)C4=CC=CC=C4
PubChem CID 139030533

Certificates

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Related Documents

References

1. Whitby RJ, Stec J, Blind RD, Dixon S, Leesnitzer LM, Orband-Miller LA, Williams SP, Willson TM, Xu R, Zuercher WJ et al..  (2011)  Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2)..  J Med Chem,  54  (7): (2266-81).  [PMID:21391689]

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