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RN-1734 - 98%, high purity , CAS No.946387-07-1, Channel blocker of TRPV4
Novel, selective TRPV4 antagonist
Basic Description Synonyms RN-1734 | 946387-07-1 | RN 1734 | 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide | RN1734 | 2,4-dichloro-N-propan-2-yl-N-[2-(propan-2-ylamino)ethyl]benzenesulfonamide | CHEMBL2324347 | 2,4-dichloro-N-isopropyl-N-(2-(isopropylamino)ethyl)benzenesul Specifications & Purity Moligand™, ≥98% Biochemical and Physiological Mechanisms RN-1734 is a selective TRPV4 antagonist. Storage Temp Store at -20°C,Argon charged Shipped In Ice chest + Ice pads Grade Moligand™ Action Type CHANNEL BLOCKER Mechanism of action Channel blocker of TRPV4 Note Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. Product Description Shipped at Room Temperature.
Application
RN-1734 has been used as a transient receptor potential vanilloid 4 (TRPV4) blocker to study its effects on differentiation of a corneal epithelial cell model, RCE1(5T5) cells.
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name 2,4-dichloro-N-propan-2-yl-N-[2-(propan-2-ylamino)ethyl]benzenesulfonamide INCHI InChI=1S/C14H22Cl2N2O2S/c1-10(2)17-7-8-18(11(3)4)21(19,20)14-6-5-12(15)9-13(14)16/h5-6,9-11,17H,7-8H2,1-4H3 InChi Key IHYZMEAZAIFMTN-UHFFFAOYSA-N Canonical SMILES CC(C)NCCN(C(C)C)S(=O)(=O)C1=C(C=C(C=C1)Cl)Cl Isomeric SMILES CC(C)NCCN(C(C)C)S(=O)(=O)C1=C(C=C(C=C1)Cl)Cl PubChem CID 3601086 Molecular Weight 353.31
Chemical and Physical Properties Solubility Chloroform (Slightly), Methanol (Slightly)
Safety and Hazards(GHS) RIDADR NONHforallmodesoftransport
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A2208456