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RN-1734 - 10mM in DMSO, high purity , CAS No.946387-07-1
Novel, selective TRPV4 antagonist
Basic Description Synonyms RN-1734 | 946387-07-1 | RN 1734 | 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide | RN1734 | 2,4-dichloro-N-propan-2-yl-N-[2-(propan-2-ylamino)ethyl]benzenesulfonamide | CHEMBL2324347 | 2,4-dichloro-N-isopropyl-N-(2-(isopropylamino)ethyl)benzenesul Specifications & Purity Moligand™, 10mM in DMSO Biochemical and Physiological Mechanisms RN-1734 is a selective TRPV4 antagonist. Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™ Product Description Shipped at Room Temperature.
Application
RN-1734 has been used as a transient receptor potential vanilloid 4 (TRPV4) blocker to study its effects on differentiation of a corneal epithelial cell model, RCE1(5T5) cells.
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 2,4-dichloro-N-propan-2-yl-N-[2-(propan-2-ylamino)ethyl]benzenesulfonamide INCHI InChI=1S/C14H22Cl2N2O2S/c1-10(2)17-7-8-18(11(3)4)21(19,20)14-6-5-12(15)9-13(14)16/h5-6,9-11,17H,7-8H2,1-4H3 InChi Key IHYZMEAZAIFMTN-UHFFFAOYSA-N Canonical SMILES CC(C)NCCN(C(C)C)S(=O)(=O)C1=C(C=C(C=C1)Cl)Cl Isomeric SMILES CC(C)NCCN(C(C)C)S(=O)(=O)C1=C(C=C(C=C1)Cl)Cl PubChem CID 3601086 Molecular Weight 353.31
Safety and Hazards(GHS) RIDADR NONHforallmodesoftransport
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