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Ro 01-6128 - ≥98%(HPLC), high purity , CAS No.302841-86-7, Allosteric modulator of mGlu 1 receptor

Item Number
R287952
Grouped product items
SKUSizeAvailabilityPrice Qty
R287952-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$149.90
R287952-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$479.90
R287952-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
R287952-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$799.90

Positive allosteric modulator of mGlu1receptors

Basic Description

Synonyms(Diphenylacetyl)-carbamic acid ethy ester | GTPL1386 | UNII-N4LS35GV3Q | Q7339198 | Ro-016128 | Ro01-6128 | Ethyl (2,2-diphenylacetyl)carbamate | Carbamic acid, (diphenylacetyl)-, ethyl ester | Ethyl N-(2,2-diphenylacetyl)carbamate | (Diphenylacetyl)-carb
Specifications & PurityMoligand™, ≥98%(HPLC)
Biochemical and Physiological MechanismsPositive allosteric modulator of mGlu1receptors. Potentiates glutamate-induced calcium release (EC50= 104.2 nM at rat mGluR1a).
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeALLOSTERIC MODULATOR
Mechanism of actionAllosteric modulator of mGlu 1 receptor

Associated Targets(Human)

GRM1 Tchem Metabotropic glutamate receptor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name ethyl N-(2,2-diphenylacetyl)carbamate
INCHI InChI=1S/C17H17NO3/c1-2-21-17(20)18-16(19)15(13-9-5-3-6-10-13)14-11-7-4-8-12-14/h3-12,15H,2H2,1H3,(H,18,19,20)
InChi Key ILSZPWZFQHSKLW-UHFFFAOYSA-N
Canonical SMILES CCOC(=O)NC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2
Isomeric SMILES CCOC(=O)NC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2
Alternate CAS 302841-86-7
PubChem CID 9903898
Molecular Weight 283.32

Certificates

C of A & Other Certificates

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
E2431445Certificate of AnalysisFeb 18, 2024 R287952
E2431446Certificate of AnalysisFeb 18, 2024 R287952
E2431447Certificate of AnalysisFeb 18, 2024 R287952
E2431448Certificate of AnalysisFeb 18, 2024 R287952
E2431449Certificate of AnalysisFeb 18, 2024 R287952
E2431450Certificate of AnalysisFeb 18, 2024 R287952
E2431451Certificate of AnalysisFeb 18, 2024 R287952
E2431452Certificate of AnalysisFeb 18, 2024 R287952

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 28.33, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 28.33, Max Conc. mM: 100

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Solution Calculators