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Ro-32-0432 , CAS No.151342-35-7, Inhibitor of protein kinase C alpha;Inhibitor of protein kinase C beta;Inhibitor of protein kinase C epsilon;Inhibitor of protein kinase C gamma
Basic Description Synonyms 151342-35-7 | ro 32-0432 | Ro-32-0432 | CHEMBL26501 | RO-320432 | (S)-3-(8-((Dimethylamino)methyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrol-2,5-dione | (S)-3-(8-((Dimethylamino)methyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl Specifications & Purity Moligand™ Grade Moligand™ Action Type INHIBITOR Mechanism of action Inhibitor of protein kinase C alpha;Inhibitor of protein kinase C beta;Inhibitor of protein kinase C epsilon;Inhibitor of protein kinase C gamma
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References Glycogen synthase kinase-3 beta inhibitor INHIBITOR ALA262 Glycogen synthase kinase-3 beta SINGLE PROTEIN Homo sapiens Glycogen synthase kinase-3 beta inhibitor INHIBITOR ALA262 Glycogen synthase kinase-3 beta SINGLE PROTEIN Homo sapiens Glycogen synthase kinase-3 beta inhibitor INHIBITOR ALA262 Glycogen synthase kinase-3 beta SINGLE PROTEIN Homo sapiens Protein kinase C epsilon inhibitor INHIBITOR ALA3582 Protein kinase C epsilon SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase SYK inhibitor INHIBITOR ALA2599 Tyrosine-protein kinase SYK SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase SYK inhibitor INHIBITOR ALA2599 Tyrosine-protein kinase SYK SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase SYK inhibitor INHIBITOR ALA2599 Tyrosine-protein kinase SYK SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase SYK inhibitor INHIBITOR ALA2599 Tyrosine-protein kinase SYK SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase SYK inhibitor INHIBITOR ALA2599 Tyrosine-protein kinase SYK SINGLE PROTEIN Homo sapiens Tyrosine-protein kinase SYK inhibitor INHIBITOR ALA2599 Tyrosine-protein kinase SYK SINGLE PROTEIN Homo sapiens
Names and Identifiers IUPAC Name 3-[(2S)-2-[(dimethylamino)methyl]-1H,2H,3H,4H-pyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione INCHI InChI=1S/C28H28N4O2/c1-30(2)15-17-12-13-32-22-11-7-5-9-19(22)24(23(32)14-17)26-25(27(33)29-28(26)34)20-16-31(3)21-10-6-4-8-18(20)21/h4-11,16-17H,12-15H2,1-3H3,(H,29,33,34)/t17-/m0/s1 InChi Key FXGHOAZJQNLNFD-KRWDZBQOSA-N Canonical SMILES CN(C[C@H]1CCn2c(C1)c(C1=C(C(=O)NC1=O)c1cn(c3c1cccc3)C)c1c2cccc1)C Isomeric SMILES CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C5C[C@H](CCN5C6=CC=CC=C64)CN(C)C PubChem CID 127757
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