Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | 303-75-3 | RO 4-1284 | 2H-Benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)- | Ro-4-1284 | 2-ethyl-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-ol | CHEMBL213814 | H2S3M5M720 | 2H-Benzo(a)quinoli |
|---|---|
| Storage Temp | Store at 2-8°C |
| Shipped In | Wet ice |
| Product Description | A reversible VMAT2 inhibitor. |
Associated Targets(Human)
SLC18A2 Tclin Synaptic vesicular amine transporter (3 Activities)
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
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SLC18A2 Tclin Synaptic vesicular amine transporter (118 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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HEK293 (82097 Activities)
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Names and Identifiers
| IUPAC Name | 2-ethyl-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-ol |
|---|---|
| INCHI | InChI=1S/C21H33NO3/c1-6-21(23)12-18-17-11-20(25-5)19(24-4)10-15(17)7-8-22(18)13-16(21)9-14(2)3/h10-11,14,16,18,23H,6-9,12-13H2,1-5H3 |
| InChi Key | TUNMGCULOKMBNJ-UHFFFAOYSA-N |
| Canonical SMILES | CCC1(CC2C3=CC(=C(C=C3CCN2CC1CC(C)C)OC)OC)O |
| Isomeric SMILES | CCC1(CC2C3=CC(=C(C=C3CCN2CC1CC(C)C)OC)OC)O |
| PubChem CID | 9345 |
| UN Number | 3077 |
| Packing Group | III |
| Molecular Weight | 347.49 |
Certificates
Certificate of Analysis(COA)
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Chemical and Physical Properties
| Solubility | Soluble in DMSO: 16 mg/mL |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS09 |
|---|---|
| Signal | Warning |
| Hazard Statements | H400:Very toxic to aquatic life |
| Precautionary Statements | P273:Avoid release to the environment. P501:Dispose of contents/container to ... P391:Collect spillage. |
| Class | 9 |