Ro 4-1284 , CAS No.303-75-3

Item Number
R346761
Grouped product items
SKUSizeAvailabilityPrice Qty
R346761-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$93.90

Basic Description

Synonyms2H-Benzo(a)quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy- | Ro 4-12884 | 2H-Benzo[a]quinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)- | 2-Hydroxy-2-ethyl-3-isobutyl-9,10-dimethoxy-1,2,3,4,5,6,
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

A reversible VMAT2 inhibitor.

Associated Targets(Human)

SLC18A2 Tclin Synaptic vesicular amine transporter (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC18A2 Tclin Synaptic vesicular amine transporter (118 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 2-ethyl-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-ol
INCHI InChI=1S/C21H33NO3/c1-6-21(23)12-18-17-11-20(25-5)19(24-4)10-15(17)7-8-22(18)13-16(21)9-14(2)3/h10-11,14,16,18,23H,6-9,12-13H2,1-5H3
InChi Key TUNMGCULOKMBNJ-UHFFFAOYSA-N
Canonical SMILES CCC1(CC2C3=CC(=C(C=C3CCN2CC1CC(C)C)OC)OC)O
Isomeric SMILES CCC1(CC2C3=CC(=C(C=C3CCN2CC1CC(C)C)OC)OC)O
PubChem CID 9345
UN Number 3077
Packing Group III
Molecular Weight 347.49

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in DMSO: 16 mg/mL

Safety and Hazards(GHS)

Pictogram(s) GHS09
Signal Warning
Hazard Statements

H400:Very toxic to aquatic life

Precautionary Statements

P273:Avoid release to the environment.

P501:Dispose of contents/container to ...

P391:Collect spillage.

Class 9

Related Documents

Solution Calculators