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Retinoic acid receptors
Ro 41-5253 - ≥99%, high purity , CAS No.144092-31-9, Antagonist of Retinoic acid receptor-α

Ro 41-5253 - ≥99%, high purity , CAS No.144092-31-9, Antagonist of Retinoic acid receptor-α

Item Number

R275860

Grouped product items
SKU	Size	Availability	Price	Qty
R275860-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$197.90

Potent, selective retinoic acid receptor antagonist

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Basic Description

Synonyms	Ro 41-5253\|144092-31-9\|LG629\|Ro-41-5253\|LG-629\|Ro415253\|4-[(E)-2-(7-heptoxy-4,4-dimethyl-1,1-dioxo-2,3-dihydrothiochromen-6-yl)prop-1-enyl]benzoic acid\|Benzoic acid, 4-(2-(7-(heptyloxy)-3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)-1-propenyl)-, S,S-
Specifications & Purity	≥99%
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of Retinoic acid receptor-α
Product Description	Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	4-[(E)-2-(7-heptoxy-4,4-dimethyl-1,1-dioxo-2,3-dihydrothiochromen-6-yl)prop-1-enyl]benzoic acid
INCHI	InChI=1S/C28H36O5S/c1-5-6-7-8-9-15-33-25-19-26-24(28(3,4)14-16-34(26,31)32)18-23(25)20(2)17-21-10-12-22(13-11-21)27(29)30/h10-13,17-19H,5-9,14-16H2,1-4H3,(H,29,30)/b20-17+
InChi Key	JEIWQRITHXYGIF-LVZFUZTISA-N
Canonical SMILES	CCCCCCCOC1=CC2=C(C=C1C(=CC3=CC=C(C=C3)C(=O)O)C)C(CCS2(=O)=O)(C)C
Isomeric SMILES	CCCCCCCOC1=CC2=C(C=C1/C(=C/C3=CC=C(C=C3)C(=O)O)/C)C(CCS2(=O)=O)(C)C
PubChem CID	5312120
Molecular Weight	484.7

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Solubility	Soluble in DMSO to 100 mM and in ethanol to 25 mM (with warming)

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