Ro 61-8048 - 98% (HPLC), high purity , CAS No.199666-03-0

Item Number

R168334

• Synonyms: 199666-03-0|Ro 61-8048|3,4-dimethoxy-N-(4-(3-nitrophenyl)thiazol-2-yl)benzenesulfonamide|Ro61-8048|3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide|Ro-61-8048|3,4-Dimethoxy-N-[4-(3-nitro-phenyl)-thiazol-2-yl]-benzenesulfonamide|CHEMB
• Specifications & Purity: ≥98%(HPLC)
• Biochemical and Physiological Mechanisms: Potent and competitive kynurenine 3-hydroxylase inhibitor (IC 50 = 37 nM). Shows antidystonic, anticonvulsant and neuroprotective effects in vivo. Orally active.
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Product Application：

Ro 61-8048 has been used as a kynurenine 3-monooxygenase (KMO) inhibitor to study its effects on nicotinamide adenine dinucleotide (NAD+) concentration in hepatocytes of mice.