Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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R288928-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $138.90 | |
R288928-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $219.90 | |
R288928-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $498.90 | |
R288928-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $899.90 | |
R288928-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,398.90 |
Inhibitor of Aβ42 fibril formation
Synonyms | [2,5'-Bi-1H-benzimidazol]-5-amine, 2'-(4-aminophenyl)- | Ro 90-7501, >=98% (HPLC) | NCGC00094031-01 | 2'-(4-Aminophenyl)-1H,3'H-[2,5'-bibenzo[d]imidazol]-5-amine | NCGC00094031-10 | SR-01000389409-1 | DTXSID80356431 | Tox21_500670 | 2-[2-(4-aminophenyl)-3 |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Inhibitor of amyloidβ42 (Aβ42) fibril assembly; reduces Aβ42-induced toxicity (EC50= 2μM). |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine |
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INCHI | InChI=1S/C20H16N6/c21-13-4-1-11(2-5-13)19-23-15-7-3-12(9-17(15)25-19)20-24-16-8-6-14(22)10-18(16)26-20/h1-10H,21-22H2,(H,23,25)(H,24,26) |
InChi Key | PAGZCEHLFCJSPV-UHFFFAOYSA-N |
Canonical SMILES | C1=CC(=CC=C1C2=NC3=C(N2)C=C(C=C3)C4=NC5=C(N4)C=C(C=C5)N)N |
Isomeric SMILES | C1=CC(=CC=C1C2=NC3=C(N2)C=C(C=C3)C4=NC5=C(N4)C=C(C=C5)N)N |
WGK Germany | 3 |
PubChem CID | 824226 |
Molecular Weight | 340.39 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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B2402249 | Certificate of Analysis | Dec 28, 2023 | R288928 |
B2402252 | Certificate of Analysis | Dec 28, 2023 | R288928 |
B2402253 | Certificate of Analysis | Dec 28, 2023 | R288928 |
B2402254 | Certificate of Analysis | Dec 28, 2023 | R288928 |
B2402255 | Certificate of Analysis | Dec 28, 2023 | R288928 |
B2402256 | Certificate of Analysis | Dec 28, 2023 | R288928 |
B2402257 | Certificate of Analysis | Dec 28, 2023 | R288928 |
B2402258 | Certificate of Analysis | Dec 28, 2023 | R288928 |
B2402259 | Certificate of Analysis | Dec 28, 2023 | R288928 |
B2402260 | Certificate of Analysis | Dec 28, 2023 | R288928 |
Solubility | Solvent:1eq. HCl, Max Conc. mg/mL: 3.4, Max Conc. mM: 10; Solvent:DMSO, Max Conc. mg/mL: 34.04, Max Conc. mM: 100 |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RIDADR | NONHforallmodesoftransport |