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RO495 - 10mM in DMSO, high purity , CAS No.1258296-60-4

Item Number

R421086

Grouped product items
SKU	Size	Availability	Price	Qty
R421086-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$199.90

JAK Inhibitors

Basic Description

Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	RO495 (CS-2667) is a potent inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2).
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	Information RO495 RO495 (CS-2667) is a potent inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2) . Targets TYK2

YES1 Tclin Tyrosine-protein kinase YES (2781 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

IUPAC Name	N-[2-[(2-amino-6-methylpyrimidin-4-yl)amino]pyridin-4-yl]-2,6-dichlorobenzamide
INCHI	InChI=1S/C17H14Cl2N6O/c1-9-7-14(25-17(20)22-9)24-13-8-10(5-6-21-13)23-16(26)15-11(18)3-2-4-12(15)19/h2-8H,1H3,(H4,20,21,22,23,24,25,26)
InChi Key	LNGDQKGREFSTHB-UHFFFAOYSA-N
Canonical SMILES	CC1=CC(=NC(=N1)N)NC2=NC=CC(=C2)NC(=O)C3=C(C=CC=C3Cl)Cl
Isomeric SMILES	CC1=CC(=NC(=N1)N)NC2=NC=CC(=C2)NC(=O)C3=C(C=CC=C3Cl)Cl
PubChem CID	57519505
Molecular Weight	389.24

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