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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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R650589-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $110.90 | |
R650589-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $170.90 | |
R650589-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $340.90 | |
R650589-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $540.90 | |
R650589-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $770.90 |
Specifications & Purity | ≥98% |
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Biochemical and Physiological Mechanisms | RO5256390 is an agonist of trace amine-associated receptor 1 ( TAAR1 ), a highly conserved G-protein-coupled receptor (GPCR) bound by endogenous trace amines. RO5256390 can be used to reduce multiple behavioral effects of agents of abuse through their ac |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | RO5256390 is an agonist of trace amine-associated receptor 1 ( TAAR1 ), a highly conserved G-protein-coupled receptor (GPCR) bound by endogenous trace amines. RO5256390 can be used to reduce multiple behavioral effects of agents of abuse through their actions on the mesocorticolimbic system. RO5256390 is a modulator of monoaminergic neurotransmission, blocks psychostimulant-induced hyperactivity and produces a brain activation pattern reminiscent of the antipsychotic agent olanzapine, suggesting antipsychotic-like properties . Form:Solid |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (4S)-4-[(2S)-2-phenylbutyl]-4,5-dihydro-1,3-oxazol-2-amine |
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INCHI | InChI=1S/C13H18N2O/c1-2-10(11-6-4-3-5-7-11)8-12-9-16-13(14)15-12/h3-7,10,12H,2,8-9H2,1H3,(H2,14,15)/t10-,12-/m0/s1 |
InChi Key | IXDKFUBXESWHSL-JQWIXIFHSA-N |
Canonical SMILES | CCC(CC1COC(=N1)N)C2=CC=CC=C2 |
Isomeric SMILES | CC[C@@H](C[C@H]1COC(=N1)N)C2=CC=CC=C2 |
PubChem CID | 24963286 |
Molecular Weight | 218.29 |
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Solubility | DMSO : 50 mg/mL (229.05 mM; Need ultrasonic) |
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RIDADR | NONHforallmodesoftransport |
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