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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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R648692-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $220.90 | |
R648692-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $350.90 | |
R648692-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $700.90 | |
R648692-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,150.90 | |
R648692-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,850.90 |
Specifications & Purity | ≥99% |
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Biochemical and Physiological Mechanisms | ROCK inhibitor-2 is a selective dual ROCK1 and ROCK2 inhibitor with IC 50 s of 17 nM and 2 nM, respectively. |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | ROCK inhibitor-2 is a selective dual ROCK1 and ROCK2 inhibitor with IC 50 s of 17 nM and 2 nM, respectively Form:Solid IC50& Target:ROCK1 17 nM (IC 50 ) ROCK2 2 nM (IC 50 ) |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | N-[(1R)-1-(3-methoxyphenyl)ethyl]-4-pyridin-4-ylbenzamide |
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INCHI | InChI=1S/C21H20N2O2/c1-15(19-4-3-5-20(14-19)25-2)23-21(24)18-8-6-16(7-9-18)17-10-12-22-13-11-17/h3-15H,1-2H3,(H,23,24)/t15-/m1/s1 |
InChi Key | JRVSFZKYQCETAH-OAHLLOKOSA-N |
Canonical SMILES | CC(C1=CC(=CC=C1)OC)NC(=O)C2=CC=C(C=C2)C3=CC=NC=C3 |
Isomeric SMILES | C[C@H](C1=CC(=CC=C1)OC)NC(=O)C2=CC=C(C=C2)C3=CC=NC=C3 |
PubChem CID | 51003130 |
Molecular Weight | 332.40 |
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Solubility | DMSO : 250 mg/mL (752.11 mM; Need ultrasonic) |
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