Rofecoxib - ≥98%, high purity , Cyclooxygenase-2 inhibitor, CAS No.162011-90-7, Cyclooxygenase-2 inhibitor

Item Number

R126597

• Synonyms: rofecoxib | 162011-90-7 | Vioxx | Ceoxx | MK 966 | 4-(4-(Methylsulfonyl)phenyl)-3-phenylfuran-2(5H)-one | refecoxib | Vioxx Dolor | MK-966 | 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one | MK-0966 | MK0966 | 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone | MK 0966 | rof
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Vioxx is a selective Cox-2 (cyclooxygenase-2) inhibitor that has anti-inflammatory properties.Selective COX-2 inhibitor. NSAID. Inhibits prostaglandin biosynthesis. Shows anti-inflammatory, analgesic, and antipyretic effects in vivo. Orally active. Blood-
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Cyclooxygenase-2 inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Rofecoxib is a COX-2 inhibitor with IC50 of 18 nM.
A selective Cox-2 inhibitor.